Occupational exposure to pesticides in mothers and fathers and risk of cancer in the offspring: A register-based case-control study from Sweden (1960–2015)

Rossides, Marios; Kampitsi, Christina-Evmorfia; Talbäck, Mats; Mogensen, Hanna; Wiebert, Pernilla; Tettamanti, Giorgio; Feychting, Maria

doi:10.1016/j.envres.2022.113820

Cited by 7 publications

(3 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, epidemiologic evidence on pesticide exposure and childhood lymphoma remains scarce due to the rarity of childhood lymphoma. A recent study from Sweden ( Rossides et al, 2022 ) found indications for an association between maternal occupational exposure to pesticides and lymphoma, but the associations were imprecisely measured (OR=1.42 (95% CI 0.78, 2.57) due to the limited number of exposed cases ( n = 12). In our ecological study, we used the average pesticide use per county as exposure under the assumption that pesticide exposures are ubiquitous ( Zhao et al, 2021 ).…”

Section: Discussionmentioning

confidence: 99%

Environmental, social and behavioral risk factors in association with spatial clustering of childhood cancer incidence

Hüls

Cor

Christensen

et al. 2023

Spatial and Spatio-temporal Epidemiology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Environmental, social and behavioral risk factors in association with spatial clustering of childhood cancer incidence

Hüls

Cor

Christensen

et al. 2023

Spatial and Spatio-temporal Epidemiology

View full text Add to dashboard Cite

“…13) Regarding pesticide exposure, an association between lymphoma or solid tumors and maternal ex posure has been suggested; however, the difference was not statistically significant. 14) Most studies investigating malignant tumors focused on oc cupational risks without specifying the exposure substances. Because certain workers can be concurrently exposed to multiple chemicals at the workplace, it is difficult to assess disease risk using individual substances, and controlling for only one factor may be ineffective.…”

Section: Paraoccupational Exposure To Parents' Occupational Hazardsmentioning

confidence: 99%

Children’s health affected by parent’s behavioral characteristics: a review

Kim,

Lee

2024

Clin Exp Pediatr

View full text Add to dashboard Cite

Exposure of an individual to occupational and environmental risk factors for a certain disease affects them and their family. Children are highly vulnerable in this setting because they are family-dependent. This review discusses diseases that occur in children according to the occupational and behavioral characteristics of their parents. Toxic agents in the home environment can affect children’s health. Maternal exposure to substances during pregnancy may directly affect fetal outcomes. The Industrial Accident Compensation Insurance Act in Korea was amended in 2023 to compensate for children’s adverse health effects due to their parents’ occupational risks. The long working hours and smoking behaviors of parents and toxic materials in the home environment are highlighted. To control for the diverse factors affecting children’s health in medical research, this review introduces directed acyclic graphs. Pediatric, occupational, and environmental medicine must collaborate to prevent childhood diseases related to environmental factors.

show abstract

“…Human exposure to pesticides has been linked to age-associated diseases, such as cancer, − particularly for chronically exposed rural workers. − Cancers of the thyroid, skin, kidneys, lymph nodes, larynge, lung, colon, and prostate have been reported to have a significantly higher incidence in pesticide-spraying farmers.…”

Section: Introductionmentioning

confidence: 99%

Exposure to Pesticides and Breast Cancer in an Agricultural Region in Brazil

Panis,

Candiotto,

Gaboardi

et al. 2024

Environ. Sci. Technol.

View full text Add to dashboard Cite

Rural workers are disproportionally exposed to pesticides and might be at an increased risk of developing chronic diseases. Here, we investigated the impact of pesticide exposure on breast cancer (BC) risk and disease profile in rural female workers. This is a case-control study that prospectively included 758 individuals. The study was conducted in the Southwest region of Paranástate in Brazil, a region characterized by familybased agriculture and intensive use of pesticides. We found that this region has a 41% higher BC diagnosis rate and 14% higher BC mortality rate than the mean rates in Brazil, as well as a pesticide trade volume about 6 times higher than the national average. We showed substantial exposure in this population and found that even women who did not work in the fields but performed equipment decontamination and clothes washing of male partners who worked in the fields had urine samples positive for glyphosate, atrazine, and/or 2,4-D. The crude association showed a significantly higher risk of BC among women exposed to pesticides (OR: 1.58, 95% CI 1.18−2.13). Adjusted analyses showed a lower and nonstatistically significant association (OR: 1.30, 95% CI 41 0.87−1.95). Stratification on disease profile showed a significantly higher risk of lymph node metastasis (adjusted OR: 2.19, 95% CI 1.31−3.72) in women exposed to pesticides. Our findings suggest that female populations exposed to pesticides are at a higher risk of developing BC with a more aggressive profile and draw attention to the need to monitor rural populations potentially exposed to pesticides in the field or at home.

show abstract

Occupational exposure to pesticides in mothers and fathers and risk of cancer in the offspring: A register-based case-control study from Sweden (1960–2015)

Cited by 7 publications

References 21 publications

Environmental, social and behavioral risk factors in association with spatial clustering of childhood cancer incidence

Environmental, social and behavioral risk factors in association with spatial clustering of childhood cancer incidence

Children’s health affected by parent’s behavioral characteristics: a review

Exposure to Pesticides and Breast Cancer in an Agricultural Region in Brazil

Contact Info

Product

Resources

About