Occupational Exposures and Chronic Airflow Limitation

Dimich‐Ward, Helen; Kennedy, Susan; Chan‐Yeung, Moira

doi:10.1155/1996/146138

Cited by 13 publications

(10 citation statements)

References 64 publications

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“…Despite the presence of chronic respiratory symptoms did not always match the level of lung function impairment, the mean values of all measured spirometric parameters, both baseline and post-bronchodilator, in dusty occupation groups were lower than their mean values in the groups of dusty occupation workers. These findings confirmed the findings from several studies performed in the last decades, that occupational exposure to inorganic or organic dust is associated with chronic airflow obstruction independent of cigarette smoking and separate from other effects of exposure such as pneumoconiosis, asthma or hypersensitivity pneumonitis [31][32][33][34].…”

Section: Discussionsupporting

confidence: 89%

Chronic Obstructive Pulmonary Disease and Occupational Exposures: Epidemiological Evidence from R. Macedonia

Минов¹,

Karadžinska-Bislimovska²,

Vasilevska³

et al. 2016

Arch Pulmonol Respir Care

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Introduction: The research found consistent associations between workplace exposures across a wide range of sectors and the development of chronic obstructive pulmonary disease (COPD) independently of or in concert with cigarette smoking. Objective: To present the epidemiological evidence for COPD among never-smoking workers from occupations associated with exposure to dusts, gases and/or fumes (dusty occupations) performed in R. Macedonia in the period 2011-2015. Methods: Prevalence and characteristics of COPD were assessed in the groups of bricklayers, cotton workers, grain workers, diary farmers, and welders. In addition, an equal group of administrative workers matched to dusty occupation workers by age and smoking status were studied as a control. Each study was performed by the same study protocol including questionnaire for respiratory symptoms in the last 12 months, baseline and post-bronchodilator spirometry and COPD diagnosis. Results: The prevalence of overall and particular respiratory symptoms in the last 12 months was higher in the dusty occupation groups as compared to their prevalence in the groups of matched administrative workers. The mean values of all measured spirometric parameters, both baseline and post-bronchodilator, were lower in the dusty occupation groups than in the groups of matched administrative workers. The prevalence of COPD was significantly higher in the dusty occupation groups as compared to its prevalence in the groups of matched administrative workers, varying from 10.7% in diary farmers, 10.8% in grain workers, 11.4% in cotton workers, 14.9% in bricklayers to 15.2% in welders. At the same time the COPD prevalence in the groups of matched administrative workers varied from 2.3% to 4.3%. COPD in all examined groups was close related to age over 45 years, as well as to duration of employment over 20 years in dusty occupation groups. Conclusion: Findings from the presented studies indicated that certain occupational exposures may be associated with the development of COPD. Findings from the presented studies also indicated a need of implementation of adequate preventive measures in order to protect respiratory health of exposed workers. asthma-like disorder) in which the prevalence of COPD attributable to workplace exposures was estimated as 15% from all COPD cases [3,4]. The research found consistent associations between workplace exposures and the development of COPD independently of or in concert with cigarette smoking, across a wide range of sectors, describing a nearly uniform pattern of exposure-response relationships. Based on the research, affected occupations include miners, construction workers, road workers, tunnel workers, welders, glass workers, metal workers, foundry workers, textile workers, farm laborers, wood workers, chemical workers, and rubber workers, i.e. a working population including millions and millions workers worldwide. In addition, existing evidence indicate that workplace exposure may influence the course of COPD as factors with important impact on...

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Section: Discussionsupporting

confidence: 89%

Chronic Obstructive Pulmonary Disease and Occupational Exposures: Epidemiological Evidence from R. Macedonia

Минов¹,

Karadžinska-Bislimovska²,

Vasilevska³

et al. 2016

Arch Pulmonol Respir Care

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“…The prevalence of moderate to severe and mild BHR was similar in all groups in our study. Borderline BHR prevalence was higher in the exposed women, with statistical significance in cleaners, confirming the findings of Dimich-Ward et al (33) that workplace exposure to dusts, fumes, vapours, and gases may lead to the development of chronic airway obstruction independent of cigarette smoking and specific exposure effects such as asthma, hypersensitivity pneumonitis or pneumoconiosis.…”

Section: Discussionsupporting

confidence: 87%

Bronchial Hyperresponsiveness in Women Cooks and Cleaners

Karadžinska-Bislimovska

Минов

Risteska-Kuc

et al. 2007

Archives of Industrial Hygiene and Toxicology

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The aim of this cross-sectional study was to assess the prevalence and characteristics of bronchial hyperresponsiveness (BHR) in 43 women cleaners (aged 26 to 57) and 37 women cooks (aged 29 to 55) and compare them with 45 controls (women office workers aged 27 to 58). The evaluation of all subjects included a questionnaire, skin prick tests to common aeroallergens, spirometry, and histamine challenge (PC20≤8 mg mL -1 ). We found higher BHR prevalence in cleaners and cooks than in office workers (30.2 % and 29.7 %, vs. 17.7 %, respectively), but statistical significance was not reached. The prevalence of mild and moderate to severe BHR was similar in all groups. Borderline BHR prevalence was significantly higher in cleaners than in controls (16.2 % vs. 6.6 %, P=0.032) whereas the difference was on the verge of significance in cooks (13.5 % vs. 6.6 %, P=0.081). Moderate to severe BHR was strongly associated with positive family history of asthma and atopy in all groups. Mild BHR was significantly associated with daily smoking in cleaners (P=0.031) and cooks (P=0.021), as well as with the duration of exposure in cleaners (P=0.038). Borderline BHR was closely related to daily smoking and duration of exposure in both cleaners and cooks. Our findings indicate an important role of workplace exposure in borderline BHR development, as well as the significant effect of smoking on mild BHR development in women cleaners and cooks.

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“…cotton, grain, wood, etc.) may lead to lung function impairment independently of any effect due to smoking [34]. A few longitudinal studies indicated accelerated annual decline of FEV1 independent of smoking in workers exposed to wood dust [35,36], cotton dust in textile workers [37,38], grain dust in grain handlers [39] and to organic dust, ammonia and endotoxin in swine http://www.mjms.mk/ http://www.id-press.eu/mjms/ production workers (40).…”

Section: Discussionmentioning

confidence: 99%

Chronic Obstructive Pulmonary Disease in Never-Smoking Female Workers Exposed to Cotton Dust

2014

Maced J Med Sci

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AIM: Textile workers in their work environment are exposed to airborne particulate from natural and synthetic origin. In the present study we aimed at assessment of prevalence and characterstics of COPD in never-smoking female workers employed at cotton weaving sector in textile manufacture. MATERIAL AND METHODS:In order to assess chronic prevalence and characteristics of chronic obstructive pulmonary disease (COPD) in textile industry we performed a cross-sectional study including 47 never-smoking female cotton workers (aged 36 to 56 years) and an equal number of never-smoking female office workers studied as a control. Evaluation of examined subjects consisted of completion of a questionnaire, baseline spirometry, and bronchodilator reversibility testing. RESULTS:We found higher prevalence of respiratory symptoms in cotton workers with significant difference for phlegm and dyspnea. Majority of the chronic respiratory symptoms in cotton workers were work-related. With exception of the mean value of forced vital capacity (FVC), the mean values of all other measured spirometric parameters in cotton workers were significantly lower than in office workers. The prevalence of COPD was significantly higher in cotton workers than in office workers (11.4% vs. 2.3%, P = 0,027). COPD in cotton workers was significantly associated with age higher than 45 years and with duration of exposure longer than 20 years. CONCLUSION:Our findings support data about relationship between occupational exposure to organic dust in textile workers and persistent airflow limitation.

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Occupational Exposures and Chronic Airflow Limitation

Cited by 13 publications

References 64 publications

Chronic Obstructive Pulmonary Disease and Occupational Exposures: Epidemiological Evidence from R. Macedonia

Chronic Obstructive Pulmonary Disease and Occupational Exposures: Epidemiological Evidence from R. Macedonia

Bronchial Hyperresponsiveness in Women Cooks and Cleaners

Chronic Obstructive Pulmonary Disease in Never-Smoking Female Workers Exposed to Cotton Dust

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