Occupational exposures and mammographic density in Spanish women

Lope, Virginia; García‐Pérez, Javier; Pérez‐Gómez, Beatriz; Pedraza-Flechas, Ana María; Alguacil, Juan; González-Galarzo, M. Carmen; Alba, Miguel Ángel Baeza; Haar, Rudolf van der; Cortés-Barragán, Rosa Ana; Pedraz-Pingarrón, Carmen; Moreo, Pilar; Santamariña, Carmen; Ederra, María; Vidal, Carmen; Salas-Trejo, Dolores; Sánchez-Contador, Carmen; Llobet, Rafael; Pollán, Marina

doi:10.1136/oemed-2017-104580

Cited by 12 publications

(13 citation statements)

References 37 publications

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“…MD is modifiable, it changes over time as well as during postmenopausal hormone therapy [11] Strong associations between MD and some factors such as postmenopausal hormone use and tamoxifen therapy [12], inversed relationships with age, postmenopausal status, and higher BMI [9] are well established. Further potential influences including association between MD and for example alcohol consumption [13], smoking, physical activity [14], night shift work [15] and other occupational exposures [16] are being investigated worldwide.…”

Section: Introductionmentioning

confidence: 99%

Cadmium and volumetric mammographic density: A cross-sectional study in Polish women

et al. 2020

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IntroductionCadmium (Cd) is a heavy metal, which is widespread in the environment and has been hypothesized to be a metalloestrogen and a breast cancer risk factor. Mammographic density (MD) reflects the composition of the breast and was proposed to be used as a surrogate marker for breast cancer. The aim of our study was to investigate association between cadmium concentration in urine and mammographic density. MethodsA cross-sectional study included 517 women aged 40-60 years who underwent screening mammography in Łó dź, Poland. Data were collected through personal interviews and anthropometric measurements. Spot morning urine samples were obtained. The examination of the breasts included both craniocaudal and mediolateral oblique views. Raw data ("for processing") generated by the digital mammography system were analysed using Volpara Imaging Software, The volumetric breast density(%) and fibrograndular tissue volume (cm 3 ) were determined. Cadmium concentration in urine was analysed using the standard ICP-MS method. ResultsAfter adjusting for key confounders including age, BMI, family breast cancer, mammographic device, season of the year of mammography, and age at menarche, an inverse association of Cd and volumetric breast density was found, which was attenuated after further adjustment for smoking. Associations of Cd with dense volume were null. ConclusionsThese findings suggest that Cd is not positively associated with breast density, a strong marker of breast cancer risk, when examined in a cross-sectional fashion.

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Section: Introductionmentioning

confidence: 99%

Cadmium and volumetric mammographic density: A cross-sectional study in Polish women

et al. 2020

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“…El estudio multicaso-control poblacional (MCC-SPAIN) que investiga la influencia de factores ambientales y su interacción con factores genéticos en tumores en España, también ha utilizado esta fuente de datos. El proyecto DDM-Occup, que forma parte de este estudio, ha publicado un análisis de la relación entre la exposición laboral a agentes higiénicos con la densidad mamaria 9 . Otras publicaciones relacionadas con MatE-mESp se detallan en su página web 10 .…”

Section: Introductionunclassified

Factores sociodemográficos y laborales relacionados con la exposición laboral a riesgos psicosociales por ocupación en España. Proyecto MatEmESp

González-Galarzo¹,

Ronda-Pérez²,

Benavides³

et al. 2019

Arch Prev Riesgos Labor

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RESUMENObjetivo: El objetivo del estudio es describir el nivel de exposición a riesgos psicosociales por ocupación en población laboral española y analizar su relación con condiciones de empleo y características sociodemográficas.Métodos: La Matriz Empleo Exposición Española (MatEmESp) es la fuente de información para la descripción de los niveles de exposición a riesgos psicosociales en 2005. Se identifican las ocupaciones con mayores niveles de exposición y se analiza su relación con condiciones de empleo y características sociodemográficas por ocupación.Resultados: Se encontraron niveles de exposición a influencia en el trabajo inferiores al punto medio de la escala (50, escala de 0 a 100) y a ritmo en el trabajo ligeramente por encima ( =46,8 y =50,8). Los niveles más elevados de exposición estaban en ocupaciones manuales, algunas cualificadas presentaban también alta inseguridad (Economistas) y ritmo de trabajo (Directores/as). Conforme disminuía el nivel de clase social y de estudios, aumentaba la inseguridad (rho=0,45 y 0,38 respectivamente), y disminuía el apoyo de los compañeros (rho=-0,46 y -0,48) y la influencia en el trabajo (rho=-0,73 y -0,63). Conforme aumentaba la proporción de extranjeros, disminuía el apoyo e influencia (rho=-0,44 y -0,43); conforme aumentaba el número de asalariados, disminuía la influencia (rho=-0,38); el aumento en contratos temporales, disminuía el apoyo de los compañeros (rho=-0,34) e influencia (rho=-0,53); y conforme aumentaba el número de horas extraordinarias, aumentaba la influencia (rho=0,49).Conclusiones: Este estudio confirma la existencia de desigualdades en la exposición a riesgos psicosociales en el trabajo en función de la ocupación y las características sociodemográficas y condiciones de empleo de la ocupación desempeñada.PALABRAS CLAVE: Estrés laboral, exposición laboral, factores socioeconómicos, empleo, clasificación, ocupaciones. SOCIODEMOGRAPHIC AND OCCUPATIONAL FACTORS RELATED TO EXPOSURE TO PSYCHOSOCIAL RISK FACTORS BY OCCUPATION IN SPAIN. THE MATEMESP PROJECT ABSTRACTObjective: The objective of the study is to describe the level of exposure to psychosocial risk factors by occupation in the Spanish working population and analyze their relationship with sociodemographic characteristics and employment conditions. Methods: The Spanish Job-Exposure Matrix (MatEmESp) is used to describe the levels of exposure to psychosocial risk factors in 2005. We identified occupations with higher levels of exposure and analysed their relationship with employment conditions and sociodemographic characteristics.Results: Levels of exposure to work influence were below the midpoint (50, on a scale from 0 to 100); for work pace, they were slightly above ( =46.8 and =50.8, respectively). The highest levels of exposure were found in manual occupations; some skilled occupations were also associated with high insecurity (economists) and work pace (managers). As social class and education decreased, insecurity increased (rho = 0.45 and 0.38 respectively), and both co-worker support ...

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“…Some studies evaluated the association between the breast density and other factors, such as residential traffic noise, education level, occupation, metabolic syndrome, socioeconomic status, and diabetes. [ 68 159 160 161 162 163 164 165 166 167 168 ] Roswall et al . [ 159 ] found no association between breast density and traffic noise exposure, either residential road or railway noise in a Danish cohort.…”

Section: Epidemiologic Factorsmentioning

confidence: 99%

The epidemiologic factors associated with breast density

2022

Journal of Research in Medical Sciences

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In recent years, some studies have evaluated the epidemiologic factors associated with breast density. However, the variant and inconsistent results exist. In addition, breast density has been proved to be a significant risk factor associated with breast cancer. Our review summarized the published studies and emphasized the crucial factors including epidemiological factors associated with breast density. In addition, we also discussed the potential reasons for the discrepant results with risk factors. To decrease the incidence and mortality rates for breast cancer, in clinical practice, breast density should be included for clinical risk models in addition to epidemiological factors, and physicians should get more concentrate on those women with risk factors and provide risk-based breast cancer screening regimens.

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Occupational exposures and mammographic density in Spanish women

Abstract: Exposure to perchloroethylene, ionising radiation, mould spores or aliphatic/alicyclic hydrocarbon solvents in occupational settings could be associated with higher MD. Further studies are needed to clarify the accuracy and the reasons for these findings.

Cited by 12 publications

References 37 publications

Cadmium and volumetric mammographic density: A cross-sectional study in Polish women

Cadmium and volumetric mammographic density: A cross-sectional study in Polish women

Factores sociodemográficos y laborales relacionados con la exposición laboral a riesgos psicosociales por ocupación en España. Proyecto MatEmESp

The epidemiologic factors associated with breast density

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