Occupational Physical Activity in Young Adults and Stroke: Was It Due to My Job?

Abstract

The association of physical activity and stroke among working young adults and vice versa has increasingly empathized in recent years. Lack of physical activity, along with many other modifiable risk factors, such as hypertension, obesity, atherosclerosis, and diabetes, contributes through vascular dysfunction to the development of adverse cerebrovascular events in the future and has always been a topic of interest in the fields of neurology and stroke rehabilitation. We wrote this review article to elaborate on this relationship in detail. This article suggests that the physical activity role in stroke development and the rehabilitation process has a diverse role, where individuals with low physically active occupations are prone to develop a stroke more readily in comparison with other workers who have a moderate amount of physical activity in their jobs; however, less mobility appeared to be harmful too soon after stroke. In addition, we elucidate the effects of physical activity on sympathetic activity and remodeling of vascular response. Alterations in the neuroendocrine system include several factors. This includes harmful changes caused by increasing levels of epinephrine and norepinephrine. These changes are seen with stress-induced cerebrovascular injury and are often elevated in post-stroke patients. In contrast, post-stroke patients engaged in physical activity may prevent these harmful neurotrophic factors by reducing the elevated levels of epinephrine and norepinephrine. However, we need more studies in the near future to further explore this association process. Therefore, we recommend more research to explore the relationship of occupation-related factors and adverse stroke outcomes.

Iron Acquisition in Mycobacterium tuberculosis

“…218 It was also demonstrated that both Ga-and Sn-PPIXs inhibit growth of Mycobacterium abscessus. 154,219 Additionally, in M. abscessus-infected macrophages, treatment with MPPs inhibited mycobacterial growth but did not exhibit toxicity towards host macrophages. Moreover, 1 μM GaPPIX inhibited intracellular M. abscessus growth to a level significantly greater than 25 μM Ga(NO 3 ) 3 ,…”

“…Both are proposed to be involved in heme uptake and are also required for the export of important Mtb cell-wall lipids, including mycolic acids. 90,[154][155][156][157][158] There are no X-ray structures of full-length MmpL3 or MmpL11, however, a structure exists for the D2 soluble domain from MmpL11, Figure 15B. 92 The MmpL11 D2 structure consists of two anti-parallel α-helices situated above the antiparallel β-sheet forming a βαββαβ fold similar to RND porter subdomains, Figure 15B.…”

<p>Behavioral Conformity of Physical Activity and Sedentary Behavior in Older Couples with One Partner Suffering from End-Stage Osteoarthritis</p>

“…They demonstrated that individuals with low physically active occupations are more prone to develop a stroke as compared to workers who have a moderate amount of PA in their jobs. 53 The second reason for this separate time window was the gender-specific imbalance with regard to housework and shopping, which was very often reported in the personal conversations about typical daily routines. It is known that even in addition to their occupation, females however engage in domestic activities more (1,42) = 4.247, p = 0.046* F (1,42) = 3.848, p = 0.056…”

High Occupational Physical Activity and cardiovascular risk factors in employees of Fomento de Construcciones y Contratas S.A. Company: a cross-sectional study

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