Occupational Risk Factors for SARS-CoV-2 Seropositivity in Healthcare Workers

Fazen, Louis E.; Abad, Queenie-Ann; Smith, Richard; Santiago, Romero; Liu, Jian; Wisnewski, Adam V.; Redlich, Carrie A.

doi:10.1097/jom.0000000000002831

Cited by 2 publications

(2 citation statements)

References 47 publications

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“…Healthcare workers (HCWs) were at increased risk of COVID-19 infection early in the COVID-19 pandemic (Gómez-Ochoa et al, 2021 ; Chou et al, 2022 ), but there is some evidence that this excess risk decreased as the pandemic moved forward (Cegolon et al, 2022 ; Cherrie et al, 2022 ; Fazen et al, 2023 ; Cherry et al, 2023a ). It is unclear whether this reflected improved workplace infection prevention and control practices or vaccination, or a combination of these factors.…”

Section: Introductionmentioning

confidence: 99%

Excess risk of COVID-19 infection and mental distress in healthcare workers during successive pandemic waves: Analysis of matched cohorts of healthcare workers and community referents in Alberta, Canada

Galarneau,

Labrèche,

Durand-Moreau

et al. 2024

Can J Public Health

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Objectives To investigate changes in risk of infection and mental distress in healthcare workers (HCWs) relative to the community as the COVID-19 pandemic progressed. Methods HCWs in Alberta, Canada, recruited to an interprovincial cohort, were asked consent to link to Alberta’s administrative health database (AHDB) and to information on COVID-19 immunization and polymerase chain reaction (PCR) testing. Those consenting were matched to records of up to five community referents (CRs). Physician diagnoses of COVID-19 were identified in the AHDB from the start of the pandemic to 31 March 2022. Physician consultations for mental health (MH) conditions (anxiety, stress/adjustment reaction, depressive) were identified from 1 April 2017 to 31 March 2022. Risks for HCW relative to CR were estimated by fitting wave-specific hazard ratios. Results Eighty percent (3050/3812) of HCWs consented to be linked to the AHDB; 97% (2959/3050) were matched to 14,546 CRs. HCWs were at greater risk of COVID-19 overall, with first infection defined from either PCR tests (OR=1.96, 95%CI 1.76–2.17) or physician records (OR=1.33, 95%CI 1.21–1.45). They were also at increased risk for each of the three MH diagnoses. In analyses adjusted for confounding, risk of COVID-19 infection was higher than for CRs early in the pandemic and during the fifth (Omicron) wave. The excess risk of stress/adjustment reactions (OR=1.52, 95%CI 1.35–1.71) and depressive conditions (OR=1.39, 95%CI 1.24–1.55) increased with successive waves during the epidemic, peaking in the fourth wave. Conclusion HCWs were at increased risk of both COVID-19 and mental ill-health with the excess risk continuing late in the pandemic.

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Section: Introductionmentioning

confidence: 99%

Excess risk of COVID-19 infection and mental distress in healthcare workers during successive pandemic waves: Analysis of matched cohorts of healthcare workers and community referents in Alberta, Canada

Galarneau,

Labrèche,

Durand-Moreau

et al. 2024

Can J Public Health

View full text Add to dashboard Cite

show abstract

“…Healthcare workers (HCWs) were at increased risk of Covid-19 infection early in the Covid-19 pandemic [1] [2], but there is some evidence that this excess risk decreased as the pandemic moved forward [3] [4] [5] [6]. It is unclear whether this reflected improved workplace infection prevention and control practices, vaccination or a combination of these factors.…”

Section: Introductionmentioning

confidence: 99%

Excess risk of Covid-19 infection and mental distress in healthcare workers during successive pandemic waves. Analysis of matched cohorts of healthcare workers and community referents in Alberta, Canada

Galarneau,

Labrèche,

Durand-Moreau

et al. 2023

Preprint

View full text Add to dashboard Cite

ObjectivesTo investigate changes in risk of infection and mental distress in healthcare workers (HCWs) relative to the community as the Covid-19 pandemic progressed.MethodsHCWs in Alberta, Canada, recruited to an interprovincial cohort, were asked consent to link to Alberta’s administrative health database (AHDB) and to information on Covid-19 immunization and polymerase chain reaction (PCR) testing. Those consenting were matched to records of up to 5 community referents (CRs). Physician diagnoses of Covid-19 were identified in the AHDB from the start of the pandemic to 31 March 2022. Physician consultations for mental health (MH) conditions (anxiety, stress/adjustment reaction, depressive) were identified from 1 April 2017 to 31 March 2022. Relative risk for HCWs was estimated for each condition, overall and for successive infection waves.Results80% (3050/3812) of HCWs consented to be linked to the AHDB: 97% (2959/3050) were matched to 14546 CRs. HCWs were at greater risk of Covid-19 overall, with first infection defined either from PCR tests or physician records They were also at increased risk for each of the three MH diagnoses. In analyses adjusted for confounding, risk of Covid-19 infection was higher than CRs early in the pandemic and during the fifth (Omicron) wave. The excess risk of stress/adjustment reactions and depressive conditions increased with successive waves during the epidemic, peaking in the 4thwave.ConclusionAdministrative health data, although not a complete reflection of infection or MH, contributed to an understanding of changing risk over time, with excess risk continuing late in the pandemic

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Occupational Risk Factors for SARS-CoV-2 Seropositivity in Healthcare Workers

Cited by 2 publications

References 47 publications

Excess risk of COVID-19 infection and mental distress in healthcare workers during successive pandemic waves: Analysis of matched cohorts of healthcare workers and community referents in Alberta, Canada

Excess risk of COVID-19 infection and mental distress in healthcare workers during successive pandemic waves: Analysis of matched cohorts of healthcare workers and community referents in Alberta, Canada

Excess risk of Covid-19 infection and mental distress in healthcare workers during successive pandemic waves. Analysis of matched cohorts of healthcare workers and community referents in Alberta, Canada

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