Occupational skin-disease data in Europe

Diepgen, Thomas L.

doi:10.1007/s00420-002-0418-1

Cited by 215 publications

(185 citation statements)

References 42 publications

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“…It has noticeable consequences (eg, health care consumption, sick leave, change of work, and impairment of health-related quality of life) for both society and the individual (2). Furthermore, hand eczema is the most common occupational skin disease (2). The most frequent type of hand eczema is contact dermatitis caused by environmental factors like skin irritants or contact allergens.…”

Section: Letter To the Editormentioning

confidence: 99%

"You get what you ask for"-impact of the wording of questions on skin disease

Meding¹,

Lidén²,

Burström³

2004

Scand J Work Environ Health

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Section: Letter To the Editormentioning

confidence: 99%

"You get what you ask for"-impact of the wording of questions on skin disease

Meding¹,

Lidén²,

Burström³

2004

Scand J Work Environ Health

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“…Occupational contact dermatitis (OCD) is one of the most common work-related illnesses in many developed countries, accounting for up to one third of all occupational diseases [1][2][3][4][5] . Data on the prevalence of OCD vary from country to country, mainly due to lack of standardised case definitions, diagnostic methods and registration systems 6,7) .…”

Section: Introductionmentioning

confidence: 99%

“…Data on the prevalence of OCD vary from country to country, mainly due to lack of standardised case definitions, diagnostic methods and registration systems 6,7) . A high prevalence has been documented in specific occupational groups, such as nurses, hairdressers, food processing workers and metal workers [1][2][3][4][5] .…”

Section: Introductionmentioning

confidence: 99%

Individual Susceptibility to Occupational Contact Dermatitis

2009

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Occupational Contact Dermatitis (OCD) is one of the most common work-related diseases. High risk occupations are in health care, hairdressing, food sector and metal industry. OCD tends to become chronic; persistent OCD often results in impaired quality of life and loss of work ability. The purpose of this article is to review the present knowledge on the factors which determine individual susceptibility to acquire OCD. Recent discoveries regarding genes involved in the skin barrier, inflammatory response and biotransformation of xenobiotics provide more insight in the individual susceptibility for OCD. Knowledge of the factors which predispose to OCD is useful in occupational health practice for the application of preventive measures and for career guidance for apprentices and workers in high risk occupations.

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“…mokre środowisko pracy (ang. wet workwoda, detergenty, środki chemiczne lub praca w rę-kawicach okluzyjnych) [4]. Wyprysk przewlekły rąk może przyjmować wiele form: zmiany rumieniowe, rumieniowo-złuszczające, nadmierne wysuszenie, rogowacenie ze złuszczaniem i towarzyszącymi rozpadlinami.…”

Section: Introductionunclassified

Alitretinoin in treatment of chronic hand eczema – mechanism of action

Matejko¹,

Krêcisz²

2016

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Przegląd Dermatologiczny 2016/5 StreSzczeniePrzewlekły wyprysk kontaktowy rąk to powszechne schorzenie, któ-re wywiera negatywny wpływ na funkcjonowanie i psychikę chorego. Stosowanie dostępnych, tradycyjnych metod leczniczych, takich jak miejscowe glikokortykosteroidy, inhibitory kalcyneuryny, fototerapia, leki immunosupresyjne, jest często niesatysfakcjonujące ze względu na brak zadowalającego rezultatu lub skutki uboczne. Alitretynoina (kwas 9-cis-retinowy) to aktywna substancja z grupy retinoidów zarejestrowana do ogólnoustrojowej terapii przewlekłego wyprysku kontaktowego rąk opornego na leczenie miejscowe. Jest agonistą zarówno receptorów RAR (receptory kwasu retinowego), jak i RXR (receptory X retinoidów) oraz pełni funkcję przeciwzapalną i immunomodulującą, ingerując w reakcję zapalną na różnych jej odcinkach. Dobra tolerancja leku oraz potwierdzona w badaniach klinicznych skuteczność terapeutyczna wskazują, że alitretynoina może być korzystną alternatywą leczniczą dla pacjentów z przewlekłym wypryskiem rąk opornym na inne formy terapii. AbStrActHand eczema is a common skin disorder with significant functional and economic impacts. Conventional therapy options, such as topical corticosteroids, calcineurin inhibitors, phototherapy and systemic immunosuppressants, often give unsatisfactory results, due to lack of efficacy or predominant adverse effects. Alitretinoin (9-cis-retinoic acid) is an active substance from the group of retinoids and is licensed as a systemic drug for chronic and severe hand eczema refractory to topical treatment. It binds with high affinity to both retinoic acid receptor (RAR) and retinoid X receptor (RXR) receptors and presents anti-inflammatory and immunomodulatory activity. Due to its good tolerance and high efficacy, demonstrated in several large clinical studies, alitretinoin may be an option for patients with severe chronic hand eczema refractory to other treatment. kontaktowe zapalenie skóry, wyprysk rąk oporny na leczenie, kwas 9-cis-retinowy, alitretynoina.

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Occupational skin-disease data in Europe

Cited by 215 publications

References 42 publications

"You get what you ask for"-impact of the wording of questions on skin disease

"You get what you ask for"-impact of the wording of questions on skin disease

Individual Susceptibility to Occupational Contact Dermatitis

Alitretinoin in treatment of chronic hand eczema – mechanism of action

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