Occurrence and antimicrobial resistance profile of Salmonella spp. in calves from the Mesoregion Sertão of Alagoas, Brazil

Abstract

The diarrhea in calves, caused by Salmonella spp., provocates serious economic damage to cattle farming. This study aimed was to verify the occurrence of diarrhea and the isolation of strains of Salmonella spp. in diarrheal feces of calves from farms located in the Sertão from the state of Alagoas municipalities, and to characterize the in vitro resistance profile of Salmonella spp. isolated against conventional antimicrobials. The study was carried out with 431 calves from 10 to 90 days old. Of the total number of animals evaluated, 111 presented a diarrhea table, being analysed 111 samples of diarrhoeal faeces. The samples were sown in enrichment broths and selective culture media and the phenotypic and molecular characterization were performed. Among the animals evaluated, 25.75% (111/431) had diarrhea. The presence of Salmonella spp. was evidenced in 13.33% (2/15) of the studied establishments. Have been isolated 2.71% (3/111) strains of Salmonella spp. and have all been shown to be resistant to Cefotaxime and sensitive to Ciprofloxacin, Gentamicin, Amoxicillin, Ampicillin and Norfloxacin. Salmonella spp. and other infectious agents associated with diarrhea were confirmed in calves in the Sertão Alagoas mesoregion. The antimicrobial potential of the tested drugs reinforces the importance of their responsible and judicious use in the treatment of Salmonellosis, not being indicated the antibiotic therapy with Cefotaxima. The treatment based on Gentamicin, Amoxicillin, Ampicillin, Ciprofloxacin and Norfloxacin in the treatment of these animals, is recommended.

Phenotypic and genotypic survey of antibiotic resistance in Salmonella enterica isolates from dairy farms in Uruguay

“…Additionally, in South America, the AMR Salmonella isolates obtained from calves differ among regions. In northeastern Brazil, the main type of resistance observed is to cefotaxime ( 22 ), whereas in southeastern Brazil, nalidixic acid and cefoxitin resistance is primarily observed to, with a high frequency of susceptibility among strains ( 23 ). In Uruguay, the main phenotypic resistance observed is to streptomycin, tetracyclines and ampicillin, with differences in susceptibility between serotypes, where Dublin is more susceptible to antibiotics than Typhimurium ( 24 ).…”