Occurrence and Detection of AmpC β-Lactamases among Enterobacteriaceae in a Tertiary Care Centre in Trivandrum

A Study on Extended Spectrum Beta Lactamse and Amp C Beta Lactamse Producing Enterobacteriaceae Isolates from Various Clinical Samples in a Tertiary Care Hospital

“…Klebsiella species was the predominant AmpC β lactamase producing agents (87.5%) followed by E.coli (12.5%). Similar results were shown in Ashish Jitendranath et al, (2018) study were 53.6% of AmpC producers belongs to Klebsiella spp. Followed by E.coli (21.4%) and Enterobacter (14.3%).…”

“…The most common Enterobacteriaceae isolate was E.coli (42.42%) followed by Klebsiella species (41.90%) and Proteus species (11.06%). Similar studies conducted by Narinder Kaur et al, (2017) and Ashish Jitendranath et al, (2018) also showed that E.coli was the most common isolate (41.6%, 54% respectively), followed by Klebsiella species (24% 32% respectively). However study conducted by Binita Bhuyan et al, (2018) showed that Klebsiella spp (55.5%) was the most common isolate among Enterobacteriaceae followed by E.coli (23.9%).…”

“…Various studies conducted in India had documented that the prevalence of ESBL production among various Gram negatives differs from 19.8%-43% (Kumar MS et al, 2006). Baral et al, (2013) had revealed that about 27.8% of their Enterobacteriaceae isolates were AmpC producers whereas study by Ashish Jitendranath et al, (2018) had documented 11.2% of Enterobacteriaceae isolates as AmpC producers. This wide variation among the ESBL and AmpC producers among Enterobacteriaceae isolates were due to varying prevalence of site and type of infections among various hospitals.…”