“…The initial increase of fever requires a 10-12.5% increase in metabolic rate for a 1°C rise in body temperature . Sickness behavior is initiated, and the animal is motivated to reduce feed intake, decrease social behavior, seek warmer environments and assume postures that minimize heat loss (Holmes and Miller, 1963;Miller, 1964;. Different fever patterns can occur depending on the pathogen and are not completely understood.…”