A novel, easy-to-use mouthwash that moisturizes the mouth and can counteract oral dryness has recently been shown to be effective. However, usersʼ subjective assessments of the usability of the mouthwash have yet to be evaluated. Thus, a questionnaire was administered to users of the experimental mouthwash to evaluate its usability. The subjects were 74 persons(59 men; mean age 43.5±21.26 years), who were divided into two groups by age: young subjects, 45 persons(45 men; mean age 24.9±4.7 years); and elderly subjects, 29 persons(14 men; mean age 64.4±7.8 years). The mouthwash was a commercially available product to which a salivation promotion component(kelp extract) and moisturizing components(betaine, sodium hyaluronate)were added. The questionnaire comprising 9 items was administered before and after use of the mouthwash. The questionnaire asked patients to use appropriate scales to rate oral dryness, saliva characteristics, halitosis, intraoral pain, sore throat, unpleasantness of the mouthwash, usability and taste of the mouthwash, and desire to use it in the future. The results showed significant improvements in oral dryness, sore throat, saliva characteristics, and halitosis after use of the mouthwash in both young and elderly persons. In addition, many generally affirmative views of the usability of the experimental mouthwash were obtained. Thus, there was a uniform evaluation across the generations that use of the experimental mouthwash is effective. The results of the questionnaire suggest that this novel mouthwash for oral dryness can be used by people of all generations.