Occurrence, Distribution, and Fate of Emerging Persistent Organic Pollutants in the Environment

Kumar, Amit; Singh, Ishan; Ambekar, Kajal

doi:10.1016/b978-0-12-822263-8.00001-4

Cited by 4 publications

(3 citation statements)

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“…2 An increasing number of unregulated emerging persistent and bioaccumulative organic compounds are also being found in the environment. 3,4 Standard protocols for monitoring halogenated POPs in various types of samples involve lengthy sample preparation steps followed by mass spectrometric analysis, typically preceded by chromatographic separations. 5 Due to the wide range of physicochemical properties displayed by different classes of POPs, a combination of LC and GC separations is usually required, with GC being the separation method of choice for (semi)volatile, nonpolar, and thermally stable analytes.…”

Section: ■ Introductionmentioning

confidence: 99%

“…All the chemicals listed in the convention, except one, are (poly)halogenated and include chlorinated (e.g., polychlorinated biphenyls PCBs, polychlorinated dibenzo-p-dioxins PCCDs), brominated (e.g., polybrominated diphenyl ethers PBDEs), and fluorinated (per- and polyfluoroakyl substances PFASs) compounds . An increasing number of unregulated emerging persistent and bioaccumulative organic compounds are also being found in the environment. , …”

Section: Introductionmentioning

confidence: 99%

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Sliding Windows in Ion Mobility (SWIM): A New Approach to Increase the Resolving Power in Trapped Ion Mobility-Mass Spectrometry Hyphenated with Chromatography

Muller,

Scholl,

Far

et al. 2023

Anal. Chem.

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Over the past decade, the separation efficiency achieved by linear IMS instruments has increased substantially, with state-of-the-art IM technologies, such as the trapped ion mobility (TIMS), the cyclic traveling wave ion mobility (cTWIMS), and the structure for lossless ion manipulation (SLIM) platforms commonly demonstrating resolving powers in excess of 200. However, for complex sample analysis that require front end separation, the achievement of such high resolving power in TIMS is significantly hampered, since the ion mobility range must be broad enough to analyze all the classes of compounds of interest, whereas the IM analysis time must be short enough to cope with the time scale of the preseparation technique employed. In this paper, we introduce the concept of sliding windows in ion mobility (SWIM) for chromatography hyphenated TIMS applications that bypasses the need to use a wide and fixed IM range by using instead narrow and mobile ion mobility windows that adapt to the analytes’ ion mobility during chromatographic separation. GC-TIMS-MS analysis of a mixture of 174 standards from several halogenated persistent organic pollutant (POP) classes, including chlorinated and brominated dioxins, biphenyls, and PBDEs, demonstrated that the average IM resolving power could be increased up to 40% when the SWIM mode was used, thereby greatly increasing the method selectivity for the analysis of complex samples.

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Section: ■ Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Sliding Windows in Ion Mobility (SWIM): A New Approach to Increase the Resolving Power in Trapped Ion Mobility-Mass Spectrometry Hyphenated with Chromatography

Muller,

Scholl,

Far

et al. 2023

Anal. Chem.

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show abstract

“…Since the end of the 19th century, several categories of emerging contaminants have emerged, largely due to scientific and analytical advances making it possible to detect them even at relatively low levels. Examples include hexabromocyclododecane (HBCD), organophosphorus flame retardants, per-and polyfluroalkyl (PFAS) substances, tetrabromobisphenol-A (TBBPA), and pharmaceutical residues (Cao et al, 2018;Coggan et al, 2019;Kumar et al, 2021;Sellier et al, 2022;Sunday et al, 2022). Pharmaceutical residues are a category of particular concern due to their broad therapeutic classes, physicochemical properties, modes of action, very large-scale distribution (e.g.…”

Section: Introductionmentioning

confidence: 99%