Occurrence, formation mechanism, detection methods, and removal approaches for chloropropanols and their esters in food: An updated systematic review

Sun, Cheng; Ni, Wei; Kou, Shunli; Wu, H.-W.; Liu, Yu; Pei, Annan; Li, Qiang

doi:10.1016/j.fochx.2022.100529

Cited by 8 publications

(6 citation statements)

References 95 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In recent years, consumer trends have shifted toward the purchase of dietary supplements, functional foods, and nutraceuticals as a result of an increased emphasis on health and disposable income (Chopra et al., 2022). Promisingly, the anthocyanin diet has great development potential and application value due to its widespread distribution in fruits and vegetables (Sun et al., 2023). The term “foodborne contaminants” refers to a group of substances that pose a threat to food safety, which can be separated into contaminants produced during food processing and environmental contaminants.…”

Section: Discussionmentioning

confidence: 99%

“…Chloropropanol is primarily synthesized via the process of acidic hydrolysis of vegetable proteins (Eisenreich et al., 2023). The primary sources of chloropropanol encompass acid‐hydrolyzed vegetable protein, soy sauce, non‐acid‐hydrolyzed food items like roasted grains and burnt malt, fermented sausages, packaging materials, and drinking water (Figure 2) (Sun et al., 2023). Numerous studies have demonstrated a significant association between the substance under investigation and adverse health effects, such as nephrotoxicity, carcinogenicity, reproductive toxicity, and neurotoxicity (Lee et al., 2017; Schultrich et al., 2020; Skamarauskas et al., 2007; Yang et al., 2020).…”

Section: Influence Of Anthocyanins On Contaminants From Food Processingmentioning

confidence: 99%

“…water (Figure 2) (Sun et al, 2023). Numerous studies have demonstrated a significant association between the substance under investigation and adverse health effects, such as nephrotoxicity, carcinogenicity, reproductive toxicity, and neurotoxicity (Lee et al, 2017;Schultrich et al, 2020;Skamarauskas et al, 2007;Yang et al, 2020).…”

Section: Protection Against Chloropropanolmentioning

confidence: 99%

See 2 more Smart Citations

Mechanism of action of anthocyanin on the detoxification of foodborne contaminants—A review of recent literature

Jiang,

Li,

Zhang

et al. 2023

Comp Rev Food Sci Food Safe

View full text Add to dashboard Cite

Foodborne contaminants refer to substances that are present in food and threaten food safety. Due to the progress in detection technology and the rising concerns regarding public health, there has been a surge in research focusing on the dangers posed by foodborne contaminants. These studies aim to explore and implement strategies that are both safe and efficient in mitigating the associated risks. Anthocyanins, a class of flavonoids, are abundantly present in various plant species, such as blueberries, grapes, purple sweet potatoes, cherries, mulberries, and others. Numerous epidemiological and nutritional intervention studies have provided evidence indicating that the consumption of anthocyanins through dietary intake offers a range of protective effects against the detrimental impact of foodborne contaminants. The present study aims to differentiate between two distinct subclasses of foodborne contaminants: those that are generated during the processing of food and those that originate from the surrounding environment. Furthermore, the impact of anthocyanins on foodborne contaminants was also summarized based on a review of articles published within the last 10 years. However, further investigation is warranted regarding the mechanism by which anthocyanins target foodborne contaminants, as well as the potential impact of individual variations in response. Additionally, it is important to note that there is currently a dearth of clinical research examining the efficacy of anthocyanins as an intervention for mitigating the effects of foodborne pollutants. Thus, by exploring the detoxification effect and mechanism of anthocyanins on foodborne pollutants, this review thereby provides evidence, supporting the utilization of anthocyanin‐rich diets as a means to mitigate the detrimental effects of foodborne contaminants.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Influence Of Anthocyanins On Contaminants From Food Processingmentioning

confidence: 99%

Section: Protection Against Chloropropanolmentioning

confidence: 99%

See 1 more Smart Citation

Mechanism of action of anthocyanin on the detoxification of foodborne contaminants—A review of recent literature

Jiang,

Li,

Zhang

et al. 2023

Comp Rev Food Sci Food Safe

View full text Add to dashboard Cite

show abstract

“…Therefore, recent advancements have developed molecular tension probes that incorporate integrin ligands and molecular linkers, such as polyethylene glycol (PEG), [19] peptide protein, [20] and DNA. [21] These innovative tools enable real-time direct measurement of cellular forces exerted at the molecular level with remarkable resolution. For instance, precise programmable DNA structures through sequence changes are primarily used as molecular tension probes because of their malleable molecular binding forces determined by a double-stranded or single-stranded DNA backbone.…”

Section: Introductionmentioning

confidence: 99%

“…For instance, precise programmable DNA structures through sequence changes are primarily used as molecular tension probes because of their malleable molecular binding forces determined by a double-stranded or single-stranded DNA backbone. [21] DNA-hairpin molecular tension probe [22] and DNA-origami, [23] utilizing twisting and unwinding forces ranging at ≈4 and 19 pN, respectively, rely on single-stranded DNA. In contrast, tension gauge tethers (TGT) relying on the rupture force of double-stranded DNA (dsDNA), which is irreversibly broken by cells when the cellular pulling force exceeds the dsDNA binding tolerance, measure 12 to 56 pN depending on the DNA sequence.…”

Section: Introductionmentioning

confidence: 99%

Selective Suppression of Integrin‐Ligand Binding by Single Molecular Tension Probes Mediates Directional Cell Migration

Han,

Lee,

Kim

et al. 2024

Advanced Science

View full text Add to dashboard Cite

Cell migration interacting with continuously changing microenvironment, is one of the most essential cellular functions, participating in embryonic development, wound repair, immune response, and cancer metastasis. The migration process is finely tuned by integrin‐mediated binding to ligand molecules. Although numerous biochemical pathways orchestrating cell adhesion and motility are identified, how subcellular forces between the cell and extracellular matrix regulate intracellular signaling for cell migration remains unclear. Here, it is showed that a molecular binding force across integrin subunits determines directional migration by regulating tension‐dependent focal contact formation and focal adhesion kinase phosphorylation. Molecular binding strength between integrin αvβ3 and fibronectin is precisely manipulated by developing molecular tension probes that control the mechanical tolerance applied to cell‐substrate interfaces. This data reveals that integrin‐mediated molecular binding force reduction suppresses cell spreading and focal adhesion formation, attenuating the focal adhesion kinase (FAK) phosphorylation that regulates the persistence of cell migration. These results further demonstrate that manipulating subcellular binding forces at the molecular level can recapitulate differential cell migration in response to changes of substrate rigidity that determines the physical condition of extracellular microenvironment. Novel insights is provided into the subcellular mechanics behind global mechanical adaptation of the cell to surrounding tissue environments featuring distinct biophysical signatures.

show abstract

Enzymatic hydrolysis of soy protein to high moisture textured meat analogue with emphasis on antioxidant effects: As a tool to improve techno-functional property

Islam

Huang

Jain

et al. 2023

Biocatalysis and Agricultural Biotechnology

View full text Add to dashboard Cite

Occurrence, formation mechanism, detection methods, and removal approaches for chloropropanols and their esters in food: An updated systematic review

Cited by 8 publications

References 95 publications

Mechanism of action of anthocyanin on the detoxification of foodborne contaminants—A review of recent literature

Mechanism of action of anthocyanin on the detoxification of foodborne contaminants—A review of recent literature

Selective Suppression of Integrin‐Ligand Binding by Single Molecular Tension Probes Mediates Directional Cell Migration

Enzymatic hydrolysis of soy protein to high moisture textured meat analogue with emphasis on antioxidant effects: As a tool to improve techno-functional property

Contact Info

Product

Resources

About