Occurrence of Multiple-Drug Resistance Bacteria and Their Antimicrobial Resistance Patterns in Burn Infections from Southwest of Iran

Abstract

Background Burn infection continues to be a major issue of concern globally and causes more harm to developing countries. This study aimed to identify the aerobic bacteriological profiles and antimicrobial resistance patterns of burn infections in three hospitals in Abadan, southwest Iran. Methods The cultures of various clinical samples obtained from 325 burn patients were investigated from January to December 2019. All bacterial isolates were identified based on the standard microbiological procedures. Antibiotic susceptibility tests were performed according to the CLSI. Results A total of 287 bacterial species were isolated burn patients.P. aeruginosa was the most frequent bacterial isolate in Gram-negative bacteria and S. epidermidis was the most frequent species isolated in Gram-positive bacteria. The maximum resistance was found to ampicillin, gentamicin, ciprofloxacin, while in Gram-negative bacteria, the maximum resistance was found to imipenem, gentamicin, ciprofloxacin, ceftazidime, and amikacin. The occurrence of multidrug resistance phenotype was as follows: P. aeruginosa (30.3 %), Enterobacter spp (11.1 %), Escherichia coli (10.5 %), Citrobacter spp (2.1 %), S. epidermidis (2.8 %), S. aureus, and S. saprophyticus (0.7 %). Conclusion Owing to the diverse range of bacteria that because burn wound infection, regular investigation, and diagnosis of common bacteria and their resistance patterns is recommended to determine the proper antibiotic regimen for appropriate therapy.

Pathogenic Characteristics and Risk Factors for ESKAPE Pathogens Infection in Burn Patients

“…In our study, the proportion of Gram-negative bacteria was slightly higher than that of Gram-positive bacteria. This distribution was also consistent with that in other hospitals in Southwest China, 18 Iran, 19 and the United Kingdom. 20 According to CHINET reports, S. aureus was the most susceptible bacteria in burn patients in China, which was consistent with our results.…”

The clinical characteristics and microbiological investigation of pediatric burn patients with wound infections in a tertiary hospital in Ningbo, China: A ten-year retrospective study

“…While most of these studies investigated adults with/ without children, little information was available on pediatric burn patients. Despite the study participants being different from the formers (Rashid et al, 2019;Mater et al, 2020;Basit et al, 2021;Cato et al, 2021;Hashemzadeh et al, 2022), the primary pathogenic bacteria detected from the burn wound of pediatric patients were also S. aureus and P. aeruginosa in the present study. In other words, Staphylococcus and P. aeruginosa were the primary bacteria infected burn wounds that are irrelevant to the host's age.…”

“…Studies have shown that S. aureus and P. aeruginosa were the leading bacteria isolated from burn wounds ( Rashid et al, 2019 ; Mater et al, 2020 ; Basit et al, 2021 ; Cato et al, 2021 ; Hashemzadeh et al, 2022 ). While most of these studies investigated adults with/without children, little information was available on pediatric burn patients.…”

Frequency and Antimicrobial Susceptibility of Bacteria Isolated From Burn Wounds: A Three Year Analysis at Burns and Plastic Surgery Center, Peshawar

“…Additionally, their antibiotic susceptibility profiles may differ from region to region, and even among different institutes and facilities, where compliance with infection control measures and antibiotic prescription practices also play important role. 7,8 In cases of burn infections, it is highly desirable that the antibiotics are used rationally and only according to the culture and sensitivity test reports. However, the culture and sensitivity / susceptibility test results take some time to become available to the clinicians.…”