Occurrence of seventeen veterinary antibiotics and resistant bacterias in manure-fertilized vegetable farm soil in four provinces of China

Wei, Ruicheng; He, Tao; Zhang, Shengxin; Zhu, Lei; Shang, Bin; Li, Zhaojun; Wang, Ran

doi:10.1016/j.chemosphere.2018.09.152

Cited by 109 publications

(45 citation statements)

References 49 publications

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“…It proved that soil nitrification was a good indicator to soils Cu contamination. However, SDZ was not list in the national soil quality standard (GB15618-2018), but the previous investigation revealed that SDZ concentrations in soil were mostly at the level of 'μg·kg −1 ' in arable soils (Table 3) [11,[33][34][35]. Moreover, the toxic endpoint of SDZ to soil PNR was kept at the level of 'mg·kg −1 ', which EC 20 was over than 4 mg·kg −1 for the tested soils in this study.…”

Section: Discussionmentioning

confidence: 52%

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Responses difference analysis of soil potential nitrification rates to Cu and sulfadiazine

Liu

Dong

et al. 2019

Environmental Pollutants and Bioavailability

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To investigate responses difference of soil potential nitrification rates (PNR) to heavy metals and antibiotics, batch toxicity experiments of Cu and sulfadiazine (SDZ) were conducted in four typical soils which were collected from different locations of China. Toxic differences of Cu and SDZ to soil PNR were evaluated based on their values of EC 20 and EC 50 calculated with logistic model. It was found that soil nitrification was a good indicator of Cu contamination in soils except for paddy soil. For SDZ, their EC X values were significantly higher than its concentration level (0.002~0.760 mg·kg -1 ) in soils. Thus, it was concluded that soil nitrification might be more sensitive to Cu than SDZ in field soil. The further Pearson correlation analysis indicated that the response of soil PNR to Cu and SDZ contamination were significantly related with soil PNR 0 and pH. ARTICLE HISTORY

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Section: Discussionmentioning

confidence: 52%

“…In addition, China is one of the largest producers and consumers of antibiotics in the world, and sulfonamides are also widely used and released into the terrestrial environment. It was found that the mean residual level of sulfonamides in vegetable farms' soils in four provinces of China was 2.61 μg·kg −1 [11].…”

mentioning

confidence: 99%

Responses difference analysis of soil potential nitrification rates to Cu and sulfadiazine

Liu

Dong

et al. 2019

Environmental Pollutants and Bioavailability

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“…When soil is mixed with manure in agricultural processes, resistance genes can be transferred either vertically or horizontally to soil microbiota. Through this process, commensals and human pathogens pick up genetic determinants such as resistance genes and virulence factors with plasmids in the already polluted soil environment ( Boxall et al, 2002 ; Ding et al, 2014 ; Forsberg et al, 2014 ; Thanner et al, 2016 ; Wei et al, 2019 ; Zhang et al, 2019 ). This assertion may additionally justify the detection of ARGs in the studied strains.…”

Section: Discussionmentioning

confidence: 99%

“…Consequently, these water bodies may be contaminated with ARG that may be incorporated into the genetic make-up of their microbiota; and whenever water from such sources is used in irrigation processes, ARG and multidrug resistant isolates are propagated unto crops, which will later on be eaten by humans and animals. This will consequently lead to a never ending cycle of transmission of ARGs to commensals and other potentially pathogenic bacteria, through the food chain and various microbiomes of the environment ( Acar et al, 2012 ; Gonzalez-Zorn and Escudero, 2012 ; Wei et al, 2019 ; Zhang et al, 2019 ). Moreover, even if waste from such farms were treated before being released into the environment, the problem will not be resolved since antibiotics are not completely deactivated in the process of waste treatment and after a while in the environment, they always revert to their initial active form ( Ding et al, 2014 ).…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, even if waste from such farms were treated before being released into the environment, the problem will not be resolved since antibiotics are not completely deactivated in the process of waste treatment and after a while in the environment, they always revert to their initial active form ( Ding et al, 2014 ). Reports of food products contaminated by multidrug resistant isolates as a consequence of extensive usage of antimicrobials in intensive animal farming are numerous ( Petersen et al, 2002 ; Rizzotti et al, 2009 ; Toomey et al, 2009 ; Shah et al, 2012 ; Drissner and Zürcher, 2014 ; Forsberg et al, 2014 ; Thanner et al, 2016 ; Wei et al, 2019 ; Zhang et al, 2019 ). Thus, such issues that could seriously impact food safety, should be addressed promptly.…”

Section: Discussionmentioning

confidence: 99%

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Complete Genomic Analysis of VRE From a Cattle Feedlot: Focus on 2 Antibiotic Resistance

et al. 2020

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Practices in intensive animal farming such as the extensive use of antimicrobials have significant impacts on the genetic make-up of bacterial communities, especially on that of human/animal commensals. In this report, whole genome sequencing of two vancomycin-resistant enterococci (VRE) isolates from a cattle feedlot in the North West Province, South Africa, was used to highlight the threats that extensive antimicrobial usage in intensive animal rearing represents for environmental microbiomes and the food chain. The genomic DNA of the studied strains was extracted using a DNA extraction kit. Whole-genome sequencing was performed through next-generation sequencing. The genomes of Enterococcus durans strain NWUTAL1 and Enterococcus gallinarum strain S52016 consisted of 3,279,618 and 2,374,946 bp, respectively with G + C contents of 40.76 and 43.13%, respectively. Antibiotic resistance genes (ARG), plasmids and virulence factors (involved in biofilm formation, colonization and copper/silver efflux system), were detected in the genomes of both strains. The presence of these genetic determinants in the studied strains is a cause for concern as they may disseminate and find their way into the food chain via horizontal gene transfer amongst bacteria of the different ecological niches. Issues of this nature cannot be undermined and are relevant as far as food safety is concerned.

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Escherichia coli isolates from vegetable farms in Addis Ababa, Ethiopia: Antimicrobial susceptibility profile and associated resistance genetic markers

Hailu,

Alemayehu,

Hailu

et al. 2024

Food Science & Nutrition

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The use of animal manure to fertilize soil is an emerging concern contributing to the transfer of antimicrobial‐resistant pathogens to vegetables. Hence, assessing antimicrobial susceptibility profile of Escherichia coli in vegetable farms is essential to design appropriate interventions against antimicrobial resistance (AMR) in the food chain. This study assessed antimicrobial resistance profile and associated genetic markers among E. coli isolated from vegetable farms fertilized with animal manure in Addis Ababa, Ethiopia. A total of 1044 samples were collected using convenience sampling: soil (n = 271), manure (n = 375), and vegetables (n = 398) from 81 vegetable farms in Addis Ababa, Ethiopia. Antimicrobial susceptibility test was conducted for 100 E. coli isolates and antimicrobial resistance genes (ARGs) were tested by polymerase chain reaction (PCR). Of the 1044 collected samples, 25.3% were positive for E. coli, with significantly higher prevalence in the manure sample and samples collected from Akaki Kality sub‐city (p < .05). The highest resistance rate was recorded for tetracycline (72%), followed by streptomycin (63%), and sulfamethoxazole +trimethoprim (56%). Multidrug resistance was detected in 61% of the E. coli isolates. The aac(3)‐IV (76.9%), bla TEM (65.4%), aadA (60.3%), tet(A) (58.3%), and sulI (51.7%) were the commonly detected resistance genes. The current study showed a high burden of antimicrobial resistance among E. coli isolated from manure‐amended vegetable farms, with potential of playing a significant role in the dissemination of antimicrobial resistance in the food chain. Efforts should be made to reduce the burden of resistant organisms and ARGs through prudent use of antimicrobials in livestock and application of appropriate composting techniques before using manure as fertilizer.

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Occurrence of seventeen veterinary antibiotics and resistant bacterias in manure-fertilized vegetable farm soil in four provinces of China

Cited by 109 publications

References 49 publications

Responses difference analysis of soil potential nitrification rates to Cu and sulfadiazine

Responses difference analysis of soil potential nitrification rates to Cu and sulfadiazine

Complete Genomic Analysis of VRE From a Cattle Feedlot: Focus on 2 Antibiotic Resistance

Escherichia coli isolates from vegetable farms in Addis Ababa, Ethiopia: Antimicrobial susceptibility profile and associated resistance genetic markers

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