Occurrences, mechanism of action, structural activity relationship and various pharmacological activities of thiadiazole and their derivatives

Gopi, Chandravadivelu; Sastry, V. Girija; Dhanaraju, Magharla Dasaratha

doi:10.1134/s207997801603002x

Cited by 2 publications

(1 citation statement)

References 79 publications

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“…In the most recent years scientific active researches target a kind of organic dyes which weren't generally synthesized for dyeing textile and different materials only but also have a great significant in hi-tech industries of electrons such as sensitized solar cells, photochromic dyes, fluorescent sensors dyes, pharmaceutical chemicals and biomedical treatment like photodynamic therapy for treating cancer disease and anti-oxidant issues [1][2][3][4]. These dyes are called functional dyes.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of some new Aryl-azo derivatives clubbed with Pyridone and evaluating their Biological Broadcast.

et al. 2020

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YNTHESIS of some new Aryl-azopyridone analogues was synthesized through coupling of diverse Diazonium salts with 1-ethyl-4-methyl-2,6-dioxopiperidine-3-carbonitrile. The proper structures for all incorporated derivatives were demonstrated to be confirmed via various physical and spectral analyses performed. The synthesized analogues were probed as cytotoxic agents toward four dissimilar cell lines, in which the results displayed persuasive activities relative to the results of antibiotic standards. In addition, the antioxidant activity of the synthesized analogues was evaluated using ABTS•+ method.

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Section: Introductionmentioning

confidence: 99%

Synthesis of some new Aryl-azo derivatives clubbed with Pyridone and evaluating their Biological Broadcast.

et al. 2020

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Multigram-scale Synthesis of Building Block Nitro-imine Derivative by Using Classical Method and Ultrasound Irradiation and Conversion to Imino-alcohol Derivative, Using Camphor as Starting Material

Silva

Araújo

Moraes

et al. 2020

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This study describes a simple multigram-scale procedure for the preparation of (E)-N-(1,7,7- trimethylbicyclo[2.2.1]heptan-2-ylidene)nitramide, nitro-imine 2, by using both classical methods and ultrasound irradiation from 1 utilizing Camphor, a natural product, as starting material. This key intermediate 2, a good building block, is useful to prepare various substances such as terpenoids, reagents for large-scale hydroxylation and amination of organic substrates, and derivatives with anticonvulsant, hypoglycemic, anti-inflammatory, antimicrobial and antiviral activities. It can be transformed into a wide range of other derivatives which can then also be employed in inorganic chemistry. In this work, another useful derivative (E)-2-((1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylidene)amino)ethanol 3 has been prepared from nitro-imine 2 on multigram-scale which also allows access to a variety of products of biological interest after suitable chemical transformations.

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Occurrences, mechanism of action, structural activity relationship and various pharmacological activities of thiadiazole and their derivatives

Cited by 2 publications

References 79 publications

Synthesis of some new Aryl-azo derivatives clubbed with Pyridone and evaluating their Biological Broadcast.

Synthesis of some new Aryl-azo derivatives clubbed with Pyridone and evaluating their Biological Broadcast.

Multigram-scale Synthesis of Building Block Nitro-imine Derivative by Using Classical Method and Ultrasound Irradiation and Conversion to Imino-alcohol Derivative, Using Camphor as Starting Material

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