OCE quantification of Poisson's ratio through 2D speckle tracking

Li, Xuan; Zaki, Farzana; Garg, Harshita; Rodriguez, J. N.

doi:10.1117/12.2503856

Cited by 2 publications

(2 citation statements)

References 5 publications

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“…Dr. Liu's group presented an adaptive Doppler analysis method to guide the choice of the time interval between signals involved in Doppler phase calculation to accurately track the nonconstant motion speed. In another presentation by the same group, 57 they proposed a novel method to quantify the Poisson's ratio by simultaneously tracking axial and lateral motion using speckle imaging and experimentally validated its capability on samples with different degrees of compressibility.…”

Section: Poster Sessionmentioning

confidence: 99%

Optical elastography and tissue biomechanics

2019

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Mechanical forces play an important role in the behavior and development of biological systems and disease at all spatial scales, from cells and their constituents to tissues and organs. Such forces have a profound influence on the health, structural integrity, and normal function of cells and organs. Accurate knowledge of cell and tissue biomechanical properties is essential to map the distribution of forces and mechanical cues in biological systems. Cell and tissue biomechanical properties are also known to be important on their own as indicators of health or disease states. Hence, optical elastography and biomechanics methods can aid in the understanding and clinical diagnosis of a wide variety of diseases. We provide a brief overview and highlight of the Optical Elastography and Tissue Biomechanics VI conference, which took place in San Francisco, February 2 and 3, 2019, as a part of Photonics West symposium.

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Section: Poster Sessionmentioning

confidence: 99%

Optical elastography and tissue biomechanics

2019

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“…Also, various algorithms based on rigid body motion applicable to intensity-based OCE data were presented. Maximization of the cross-correlation coefficient between the unloaded image and a moving window over the loaded image is a commonly used method [29], [34]. A similar approach is applied in digital image correlation [32] and digital volume correlation techniques [35].…”

Section: Introductionmentioning

confidence: 99%

Quantitative Optical Coherence Elastography: A Novel Intensity-Based Inversion Method Versus Strain-Based Reconstructions

Krainz

Sherina

Hubmer

et al. 2023

IEEE J. Select. Topics Quantum Electron.

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Many diseases like cancer or atherosclerosis bear micro-scale tissue stiffness changes, which can be visualised by optical coherence elastography (OCE). OCE is a promising research field, where a growing number of publications present qualitative displacement maps. Quantitative OCE results have also been presented, but still lack high precision and good reproducibility, which are important for clinical applications. In this work, we compare three reconstruction methods for the Young's modulus in intensity-based quasi-static compressional OCE: uniaxial analysis, strain map based reconstruction facilitating a particle tracking improved optical flow (EOFM), and a novel image-based inverse reconstruction method (IIM). The quality of the proposed reconstruction methods is investigated by comparing their performance on twelve silicone elastomer phantoms with inclusions of varying size and stiffness. While the uniaxial reconstruction is strongly affected by lateral motion, EOFM is capable of deriving precise strain maps from consecutive OCT images during compression. However, for a valid Young's modulus reconstruction additional stress map information is required. IIM performs best, precisely reconstructing Young's modulus of inclusion and background, closely corresponding to separately determined ground truth values. The method offers a significant improvement of the relative error by a factor of 3.5 compared to uniaxial and strain-based analysis.

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OCE quantification of Poisson's ratio through 2D speckle tracking

Cited by 2 publications

References 5 publications

Optical elastography and tissue biomechanics

Optical elastography and tissue biomechanics

Quantitative Optical Coherence Elastography: A Novel Intensity-Based Inversion Method Versus Strain-Based Reconstructions

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