Ochratoxin A and Aflatoxin B1 Detection in Laying Hens for Omega 3-Enriched Eggs Production

Bozzo, Giancarlo; Pugliese, Nicola; Samarelli, Rossella; Schiavone, Antonella; Dimuccio, Michela Maria; Circella, Elena; Bonerba, Elisabetta; Ceci, Edmondo; Camarda, Antonio

doi:10.3390/agriculture13010138

Cited by 3 publications

(1 citation statement)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Consequently, it is possible to suggest that the degree and rate of exposure, as well as tissue damage may be also modified; (b) The toxicity of aflatoxins varies according to animal species, age, and sex [ 54 ]. Apart from their toxicity to humans, there are species more susceptible to the mycotoxin actions, such as the avian ones [ 55 ]. Then, some differences regarding experimental results could be attributed to such parameters; and (c), the absence of a dose-response curve and longer schedule of treatments could limit the mechanistic conclusions regarding the toxic effects of AFB 1 .…”

Section: Resultsmentioning

confidence: 99%

Intermittent Exposure to Aflatoxin B1 Did Not Affect Neurobehavioral Parameters and Biochemical Markers of Oxidative Stress

et al. 2023

View full text Add to dashboard Cite

Aflatoxin B1 (AFB1) is the most common toxic mycotoxin that contaminates food. The treatment of its intoxication and the management of contaminations are a constant subject of health agendas worldwide. However, such efforts are not always enough to avoid population intoxication. Our objective was to investigate whether intermittent exposure to AFB1 would cause any impairment in biochemical and behavioral parameters, intending to simulate an irregular consumption. Male Wistar rats received four AFB1 administrations (250 μg/kg) by intragastric route separated by a 96-h interval. Toxicity was evaluated using behavioral tests (open field, object recognition, nest construction, marble burying, and splash test), biochemical markers of oxidative stress (cerebral cortex, hippocampus, liver, and kidneys), and plasma parameters of hepatic and renal functions. The intermittent exposure caused no modification in body weight gain as well as in organ weight. Both control and AFB1 groups presented similar profiles of behavior to all tests performed. Furthermore, AFB1 administrations alter neither antioxidant defenses nor markers of oxidation in all assayed tissues and in the plasma markers of hepatic and renal functions. Therefore, AFB1 intermittent administration did not cause its common damage from exposure to this toxicant, which must be avoided, and additional studies are required.

show abstract

Section: Resultsmentioning

confidence: 99%

Intermittent Exposure to Aflatoxin B1 Did Not Affect Neurobehavioral Parameters and Biochemical Markers of Oxidative Stress

et al. 2023

View full text Add to dashboard Cite

show abstract

Effect of Dietary Supplementation of Mycotoxin Adsorbent on Laying Performance and Oviduct Health of Laying Hens in Aflatoxin B1 Exposed

Wei,

Sun,

Sun

et al. 2024

Agriculture

View full text Add to dashboard Cite

Aflatoxin contamination causes huge economic losses in animal husbandry by inhibiting growth and performance. The addition of mycotoxin binders to contaminate diets has been widely used for mycotoxin removal. Bentonite and yeast cell walls have received increasing attention as efficient and low-cost adsorbents. This study utilizes a mycotoxin adsorbent (MAB) to bind Aflatoxin B1 (AFB1) in feed. The trial was a randomized trial design, with 240 forty-three-week-old Hy-line Brown laying hens allocated to four groups, and with 80 birds in each group. The three diets used in the experiment were: (1) control diet; (2) control diet + 0.2 mg/kg AFB1; (3) control diet+ 0.2 mg/kg AFB1 + 2.0 g/kg MAB. All laying hens were fed a basal diet for one week. The feeding trial lasted for 12 weeks followed by a 1-week adaptation phase. The results show that laying hens fed the AFB1-contaminated diet had decreased performance and egg quality and reduced oviduct index and length. Blood biochemical parameters show that AFB1 leads to increased serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. Compared to the control diet groups, exposure to the AFB1-contaminated diet resulted in liver and uterine tissue damage, mainly manifested by inflammatory infiltration. Compared with AFB1-contaminated diets, liver and uterine damage was alleviated with the AFB1 + MAB diet and partially restored to control levels. At the same time, we also observed that AFB1 treatment up-regulated the expression of Interferon-α (IFN-α), CASPASE-3, and CASPASE-8 in the uterus of laying hens, but this phenomenon was alleviated after adding the MAB. Therefore, under the experimental conditions, supplementation of MAB in AFB1-contaminated hen diets was an effective intervention to reduce aflatoxin toxicity.

show abstract

Ochratoxin A in Poultry Supply Chain: Overview of Feed Occurrence, Carry-Over, and Pathognomonic Lesions in Target Organs to Promote Food Safety

Bonerba,

Manfredi,

Dimuccio

et al. 2024

Toxins

View full text Add to dashboard Cite

Ochratoxin A (OTA) is a mycotoxin produced by fungi species belonging to the genera Aspergillus spp. and Penicillium spp. The proliferation of OTA-producing fungal species may occur due to inadequate practices during both the pre-harvest and post-harvest stages of feed. Consequently, poultry species may be exposed to high concentrations of this mycotoxin that can be transferred to animal tissues due to its carry-over, reaching dangerous concentrations in meat and meat products. Therefore, this review aims to propose a comprehensive overview of the effects of OTA on human health, along with data from global studies on the prevalence and concentrations of this mycotoxin in avian feeds, as well as in poultry meat, edible offal, and eggs. Moreover, the review examines significant gross and histopathological lesions in the kidneys and livers of poultry linked to OTA exposure. Finally, the key methods for OTA prevention and decontamination of feed are described.

show abstract

Ochratoxin A and Aflatoxin B1 Detection in Laying Hens for Omega 3-Enriched Eggs Production

Cited by 3 publications

References 51 publications

Intermittent Exposure to Aflatoxin B1 Did Not Affect Neurobehavioral Parameters and Biochemical Markers of Oxidative Stress

Intermittent Exposure to Aflatoxin B1 Did Not Affect Neurobehavioral Parameters and Biochemical Markers of Oxidative Stress

Effect of Dietary Supplementation of Mycotoxin Adsorbent on Laying Performance and Oviduct Health of Laying Hens in Aflatoxin B1 Exposed

Ochratoxin A in Poultry Supply Chain: Overview of Feed Occurrence, Carry-Over, and Pathognomonic Lesions in Target Organs to Promote Food Safety

Contact Info

Product

Resources

About