Ocorrência de dermatófitos em amostras de unhas, pés e mãos coletadas de estudantes universitários

Siqueira, Emersom Roberto; Ferreira, Joseane Cristina; Maffei, Carlos Eduardo Moreira; Candido, Renato

doi:10.1590/s0037-86822006000300008

Cited by 17 publications

(9 citation statements)

References 6 publications

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“…These cultures were interpreted as proof of the diagnostic hypothesis of mycosis. Verification of 47.8% of positive cultures is in agreement with the range of positivity that has been reported in the literature for these types of mycoses, which vary between 20.8% and 60%, when culture is considered a diagnostic criterion 40,50 . Several causes have been indicated to justify the low rate of fungi recovery in culture media, as registered in this study.…”

Section: Resultssupporting

confidence: 87%

Fungal agents in different anatomical sites in Public Health Services in Cuiabá, state of Mato Grosso, Brazil

Araújo

Fontes

Júnior

et al. 2012

Rev. Inst. Med. trop. S. Paulo

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SUMMARYIntroduction: A contribution to the regional epidemiological profile of the most common fungal agents in Public Health Services in Cuiabá, state of Mato Grosso, including university hospitals and polyclinics. Methods: Clinical specimens (n = 1,496) from 1,078 patients were collected, submitted to direct mycological exam (potash or stick tape method) and cultured in specific mediums. Dermatophytic and non-dermatophytic agents were identified according to micromorphology (Ridell technique). Results: The majority of the 1,496 specimens were skin (n = 985) and nail exams (n = 472). Of the 800 positive cultures, 246 (30.8%) corresponded to dermatophytes and 336 (42%) to yeasts of the genus Candida, 190 (23.7%) to other yeasts, 27 (3.4%) to non-dermatophytic filamentous fungi and one (0.1%) the agent of subcutaneous mycosis. Lesions considered primary occurred in greater numbers (59.5%) than recurrent lesions (37.4%), with a greater concentration of positivity occurring on the arms and legs. Conclusions: Comorbidities, allergies and diabetes mellitus were conditions associated with greater positivity in direct mycological exams and cultures. Positive culture was considered a definitive diagnosis of fungal infection and confirmed 47.8% of diagnostic hypotheses.

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Section: Resultssupporting

confidence: 87%

Fungal agents in different anatomical sites in Public Health Services in Cuiabá, state of Mato Grosso, Brazil

Araújo

Fontes

Júnior

et al. 2012

Rev. Inst. Med. trop. S. Paulo

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“…A total of 20 clinical isolates from nails and skin (four of T. rubrum and 16 of T. mentagrophytes) maintained in Sabouraud dextrose agar, at room temperature, until tested were included in this study 22 . Candida parapsilosis ATCC 22019 was the reference strain.…”

Section: Methodsmentioning

confidence: 99%

Dermatophyte susceptibilities to antifungal azole agents tested in vitro by broth macro and microdilution methods

Siqueira

Ferreira

Pedroso

et al. 2008

Rev. Inst. Med. trop. S. Paulo

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SUMMARYThe in vitro susceptibility of dermatophytes to the azole antifungals itraconazole, fluconazole and ketoconazole was evaluated by broth macro and microdilution methods, according to recommendations of the CLSI, with some adaptations. Twenty nail and skin clinical isolates, four of Trichophyton mentagrophytes and 16 of T. rubrum were selected for the tests. Itraconazole minimal inhibitory concentrations (MIC) varied from < 0.03 to 0.25 µg/mL in the macrodilution and from < 0.03 to 0.5 µg/mL in the microdilution methods; for fluconazole, MICs were in the ranges of 0.5 to 64 µg/mL and 0.125 to 16 µg/mL by the macro and microdilution methods, respectively, and from < 0.03 to 0.5 µg/mL by both methods for ketoconazole. Levels of agreement between the two methods (± one dilution) were 70% for itraconazole, 45% for fluconazole and 85% for ketoconazole. It is concluded that the strains selected were inhibited by relatively low concentrations of the antifungals tested and that the two methodologies are in good agreement especially for itraconazole and ketoconazole.

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“…3 In Brazil, surveys by Siqueira et al (2006) and Brilhante et al (2000) 5 showed that the prevalence of dermatophytoses among cutaneous lesions ranges from 18.2 to 23.2%. 4,5 …”

Section: Introductionmentioning

confidence: 99%

Clinical, epidemiological, and therapeutic profile of dermatophytosis

Pires

Cruz

Lobato

et al. 2014

An. Bras. Dermatol.

104

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BACKGROUNDThe cutaneous mycoses, mainly caused by dermatophyte fungi, are among the most common fungal infections worldwide. It is estimated that 10% to 15% of the population will be infected by a dermatophyte at some point in their lives, thus making this a group of diseases with great public health importance.OBJECTIVETo analyze the clinical, epidemiological, and therapeutic profile of dermatophytosis in patients enrolled at the Dermatology service of Universidade do Estado do Pará, Brazil, from July 2010 to September 2012.METHODA total of 145 medical records of patients diagnosed with dermatophytosis were surveyed. Data were collected and subsequently recorded according to a protocol developed by the researchers. This protocol consisted of information regarding epidemiological and clinical aspects of the disease and the therapy employed.RESULTSThe main clinical form of dermatophyte infection was onychomycosis, followed by tinea corporis, tinea pedis, and tinea capitis. Furthermore, the female population and the age group of 51 to 60 years were the most affected. Regarding therapy, there was a preference for treatments that combine topical and systemic drugs, and the most widely used drugs were fluconazole (systemic) and ciclopirox olamine (topical).CONCLUSIONThis study showed the importance of recurrent analysis of the epidemiological profile of dermatophytosis to enable correct therapeutic and preventive management of these conditions, which have significant clinical consequences, with chronic, difficult-totreat lesions that can decrease patient quality of life and cause disfigurement.

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Ocorrência de dermatófitos em amostras de unhas, pés e mãos coletadas de estudantes universitários

Cited by 17 publications

References 6 publications

Fungal agents in different anatomical sites in Public Health Services in Cuiabá, state of Mato Grosso, Brazil

Fungal agents in different anatomical sites in Public Health Services in Cuiabá, state of Mato Grosso, Brazil

Dermatophyte susceptibilities to antifungal azole agents tested in vitro by broth macro and microdilution methods

Clinical, epidemiological, and therapeutic profile of dermatophytosis

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