Ocotea quixos, American cinnamon

Naranjo, Plutarco; Kijjoa, Anake; Giesbrecht, Astrea Mennucci; Gottlieb, Otto R.

doi:10.1016/0378-8741(81)90038-6

Cited by 30 publications

(17 citation statements)

References 3 publications

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“…The oil lacked safrole, which is actually the main constituent of sassafras oil from O. pretiosa. Contrary to previous reports, 10 the presence of o-methoxycinnamaldehyde was negligible, while cinnamic acid was not detected. If compared to the essential oil obtained from the floral calices of the same plants collected at the same time, 11 a different phenylpropanoid pattern was shown.…”

Section: Resultscontrasting

confidence: 85%

“…6,7 It has been esteemed for its aromatic properties since the time of the Incas 8 and appreciated as an appetizer, eupeptic, disinfectant and local anaesthetic. 9,10 Its leaves are also traditionally used to make an antidiarrhoeic infusion. Every 2 years the tree produces big, woody flower calices, locally called 'ishpingo' (Quechua, Shuar, Cofan), 'ocatuhue viqui' (Huaorani) or 'flor de canela' due to their cinnamon-like smell, which are traditionally used by the indigenous people of the Amazon as a cinnamon-substitute spice and to aromatize sweets and cakes.…”

Section: Introductionmentioning

confidence: 99%

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Essential oil of wildOcotea quixos (Lam.) Kosterm. (Lauraceae) leaves from Amazonian Ecuador

Sacchetti

Guerrini

Noriega³

et al. 2006

Flavour Fragr. J.

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The essential oil extracted by steam distillation from the leaves of wild Ocotea quixos (Lauraceae) was analysed by GC and GC-MS. Sixty-one compounds were identified, representing 93.6% of the total detected. The main components were β β β β β-caryophyllene (15.1%), cinnamyl acetate (11.4%), sabinene (7.6%), geranial (5.6%) and transcinnamaldehyde (5.1%). Remarkable differences were noted with respect to the essential oil previously obtained from the flower calices of the same plant.

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Section: Resultscontrasting

confidence: 85%

Section: Introductionmentioning

confidence: 99%

Essential oil of wildOcotea quixos (Lam.) Kosterm. (Lauraceae) leaves from Amazonian Ecuador

Sacchetti

Guerrini

Noriega³

et al. 2006

Flavour Fragr. J.

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“…Sm., Cryptocarya canelilla Kunth), (Lauraceae) is an aromatic plant abundant in the Amazon region, where it is commonly known as ‘casca‐preciosa’ (precious bark). This plant is an important and historically interesting species in the Amazon forest because it was confused with cinnamon trees ( Cinnamomum zeylanicum Blume) during the 1540 voyage of Pizarro and Orellana from the Andes to the Amazon estuary and during Humbolt and Bonpland’s 1800 expedition in the Orinoco River basin to find the ‘famous cinnamon’ [1].…”

Section: Introductionmentioning

confidence: 99%

Cardiovascular effects of 1-nitro-2-phenylethane, the main constituent of the essential oil of Aniba canelilla, in spontaneously hypertensive rats

Interaminense

Siqueira

Xavier

et al. 2010

Fundamental &Amp; Clinical Pharmacology

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This study investigated the cardiovascular responses to the essential oil of Aniba canelilla (EOAC) and its main constituent 1-nitro-2-phenylethane (NP) in spontaneously hypertensive rats (SHRs). In anesthetized SHRs, intravenous (i.v.) bolus injections of EOAC (1-20 mg/kg) or NP (1-10 mg/kg) elicited dose-dependent hypotensive and bradycardiac effects, which were characterized in two periods (phases 1 and 2). The first rapid component (phase 1) evoked by EOAC and NP both at 10 mg/kg was absent after left ventricle injection, fully abolished by bilateral vagotomy and perineural treatment of both cervical vagus nerves with capsaicin (250 μg/mL) while remained unaltered by i.v. pretreatment with capsazepine (1 mg/kg) or ondansetron (30 μg/kg). In conscious SHRs, NP (5 and 10 mg/kg, i.v.) evoked rapid hypotensive and bradycardiac effects (phase 1) that were fully abolished by methylatropine (1 mg/kg, i.v.) pretreatment. In rat endothelium-containing mesenteric preparations, increasing concentrations (0.1-1000 μg/mL) of EOAC and NP relaxed the phenylephrine-induced contraction in a concentration-dependent manner. It is concluded that NP induces a vago-vagal bradycardiac and depressor reflex (phase 1) that apparently results from the stimulation of vagal pulmonary rather than cardiac C-fiber afferents. This effect does not appear to involve activation of either vanilloid TPRV(1) or 5-HT(3) receptors located on vagal sensory nerves. The phase 2 hypotensive response to i.v. NP seems to result, at least in part, from its direct vasodilatory effect on the peripheral smooth muscle. All in vivo and in vitro effects of EOAC are mostly attributed to the actions of its main constituent NP.

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“…Vilegas et al (12) submitted a sample of A. canelilla to supercritical gas (CO 2 ) extraction and identified 97% of phenylpropanes and sesquiterpenes, of which 1-nitro-2-phenylethane corresponded to 71.2% of the oil. According to Oger et al (13), 1-nitro-2-phenylethane possesses toxicity against Candida albicans, and is also responsible to the cinnamon smell of the bark and leaves of A. canelilla (14). The second major compound of this oil was methyl eugenol, which was reported to possess antispasmodic activity (15).…”

Section: Introductionmentioning

confidence: 97%

Phytochemical and Toxicological Evaluations of the Essential Oil From the Bark ofAniba canellila(H.B.K.) Mez.

Sousa

Araújo

Pereira

et al. 2009

Journal of Essential Oil Research

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Due to its therapeutic action, the phytochemical study of the essential oil of Aniba canelilla H.B.K Mez. (Lauraceae) and its toxicological preclinical trial were evaluated. The essential oil extracted from the bark (OEAC) yielded 1.0% and the major constituents were 1-nitro-2-phenylethane (52.9%) and methyl eugenol (38.7%), both identified by GC/ MS and GC-FID. The observed LD 50 (oral) was 720 ± 66.4 mg/kg. The doses used in the subacute toxicity study (1/10 and 1/20 of the LD 50 ) were administered in rats for 30 days, and the biochemical (glucose, urea, creatinine, triglycerides, cholesterol, glutamic-oxaloacetic transaminase, glutamic-pyruvic transaminase and alkaline phosphatase) and hematological (erythrocytes, leukocytes and platelets counts, blood hemoglobin concentration, hematocrit and mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration) parameters were observed. The results suggested that the A. canellila oil presented low toxicity in rats, according to the used dosages.

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Ocotea quixos, American cinnamon

Cited by 30 publications

References 3 publications

Essential oil of wildOcotea quixos (Lam.) Kosterm. (Lauraceae) leaves from Amazonian Ecuador

Essential oil of wildOcotea quixos (Lam.) Kosterm. (Lauraceae) leaves from Amazonian Ecuador

Cardiovascular effects of 1-nitro-2-phenylethane, the main constituent of the essential oil of Aniba canelilla, in spontaneously hypertensive rats

Phytochemical and Toxicological Evaluations of the Essential Oil From the Bark ofAniba canellila(H.B.K.) Mez.

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