OCT measurements on the foveal and perifoveal retinal thickness on diabetic patients after phacoemulsification and IOL implantation

Abstract

Purpose The first aim (I.) was to measure the change of macular thickness in diabetic (DM group) and nondiabetic patients (NORMAL group), the values of operated eye (OP) were compared I.A.) to the fellow, non-operated eye (CONTROL) and I.B.) to preoperative baseline value of the operated eye (PRE). The second aim (II.) was to compare postoperative macular thickening of DM group to NORMAL group eyes. Methods Retinal thickness values of the foveal and perifoveal (fovea þ 3.0 mm, fovea þ 6.0 mm) sectors and the minimum values were measured in a prospective study using optical coherence tomography (OCT) in 18 eyes of 18 diabetic patients and 53 eyes of 53 nondiabetic patients who underwent uneventful cataract surgery. Data were collected on the preoperative day and on postoperative 1, 7, 30, and 60 days. Student's t-test was used for statistical analysis.Results No significant change of the thickness values could be measured one day after surgery. However, a significant increase could be detected on the postoperative 7, 30, and 60 days in the perifoveal 3.0 mm and 6.0 mm sectors either calculated alone or averaged together with the foveal values. The initial (preoperative) average value of 232.7 ± 3.5 lm (mean ± SEM, n ¼ 144) in the 6.0 mm perifoveal region increased to 246.0 ± 8.2 lm (mean ± SEM, n ¼ 120, P ¼ 0.032) one week, to 249.9±5.1 lm (n ¼ 112, P ¼ 0.017) one month, and to 249.5±6.2 lm (n ¼ 104, P ¼ 0.009) 2 months after surgery. DiscussionOur results indicate that diabetes did not influence significantly the thickening of the macular regions after uncomplicated cataract surgery.

Comprehensive review of the effects of diabetes on ocular health

“…Several studies, including the ETDRS, did not find an association between clinically significant macular edema and cataract extraction [121,127–129]. Biró and Balla measured macular thickness using optical coherence tomography (OCT) in diabetic and non-diabetic eyes following phacoemulsification and found that there was no significant difference in macular edema between the two groups [130]. Similarly, Dowler et al, failed to uncover a significant difference between ECCE and phacoemulsification vis-à-vis the progression of their patients’ macular edema or retinopathy [131].…”

Randomized controlled trial on the safety of intracameral cephalosporins in cataract surgery

“…Kim et al showed a mean 9-μm increase in CPT at 12 weeks 21. Biró et al advocated using the 6-mm perifoveal retinal thickness for a more sensitive measure for detecting macular edema 23,24. They showed 5.3% increase in 6-mm perifoveal values at 2 months after phacoemulsification.…”

Optical coherence tomography in patients undergoing cataract surgery

“…In another study, Biró et al (23) compared the CFT of 18 eyes of diabetic patients with 36 eyes of nondiabetic patients using SD-OCT preoperatively and at 1, 7, 30, and 60 days post-op, with the contralateral eye acting as the control. Patients with any other ophthalmic pathologies were excluded, as well as those with severe NPDR or with proliferative DR. A significant increase was noted in the CFT in both the groups with DM and without DM as compared with their respective controls.…”