We present a model of three fermion generations with SU(3) ×
U(1) gauge symmetry constructed from the complex Clifford algebra ℂℓ(8), within which the discrete group S
3 acts as a family symmetry. ℂℓ(8) corresponds to the algebra of complex linear maps from the (complexification of the) Cayley-Dickson algebra of sedenions, 𝕊, to itself. The automorphism group of 𝕊 is G
2
×
S
3. We interpret S
3, suitably embedded into ℂℓ(8), as a family symmetry. The gauge symmetry SU (3) ×
U (1) is invariant under S
3. First-generation states are represented in terms of two even ℂℓ(8) semi-spinors, obtained from two minimal left ideals, related to each other via the order-two S
3 symmetry. The remaining two generations are obtained by applying the S
3 symmetry of order-three to the first generation, resulting in three linearly independent generations.