“…For instance, Prakash et al indicated the maximum differences of R-squared variability estimation value (stepwise regression analysis model in one Zernike polynomial) in the trefoil, coma, and tetrafoil values between idiopathic amblyopic eye and normal fellow eye [(8)]. However, in some studies, the results have varied, probably because they performed measurements using equipment based on different theories, with lower resolution, or from an older generation [(1,9,10,12,13)]. Nevertheless, the HOA affects the image quality; therefore, the HOA, particularly the tetrafoil value measured using iDesign, may influence the amblyopic eye recovery speed.…”