2000
DOI: 10.1046/j.1463-5224.2000.00106.x
|View full text |Cite
|
Sign up to set email alerts
|

Ocular and periocular manifestations of leishmaniasis in dogs: 105 cases (1993–1998)

Abstract: The purpose of this retrospective study was to determine the prevalence, type, and prognosis of ocular lesions associated with leishmaniasis in dogs. One hundred and five dogs (24.4% of all cases of leishmaniasis diagnosed during the study period) had ocular or periocular leishmaniasis, and 16 dogs (15.2% of ocular cases) had only ocular lesions and systemic signs were not apparent. Anterior uveitis was the most common manifestation and other prevalent findings included blepharitis and keratoconjunctivitis. Se… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

8
96
1
29

Year Published

2007
2007
2022
2022

Publication Types

Select...
5
4

Relationship

0
9

Authors

Journals

citations
Cited by 83 publications
(134 citation statements)
references
References 18 publications
8
96
1
29
Order By: Relevance
“…The ophthalmologic lesions were unresponsive to therapy despite resolution of the other systemic and cutaneous manifestations of this disease, which led to a fine needle aspirate of the anterior eye and isolation of Leishmania sp. This rare finding is in contrast to canine disease where 25% of canine VL cases have ocular manifestations [39], with a range of 16-80% in various case studies [7,19,30,40,47]. In the most recent review, a granulomatous inflammatory infiltrate was found and in 32 of 120 eyes (26.6%) with parasites identified immunohistochemically within the globe [39].…”
Section: Endo-ocular Parasitismmentioning
confidence: 96%
“…The ophthalmologic lesions were unresponsive to therapy despite resolution of the other systemic and cutaneous manifestations of this disease, which led to a fine needle aspirate of the anterior eye and isolation of Leishmania sp. This rare finding is in contrast to canine disease where 25% of canine VL cases have ocular manifestations [39], with a range of 16-80% in various case studies [7,19,30,40,47]. In the most recent review, a granulomatous inflammatory infiltrate was found and in 32 of 120 eyes (26.6%) with parasites identified immunohistochemically within the globe [39].…”
Section: Endo-ocular Parasitismmentioning
confidence: 96%
“…25,26 Ocular disease is quite common in CanL and can be the only or the main clinical manifestation in 3.7% to 16% of the affected dogs. 22,73,93,110 Ocular pathology in leishmanial dogs has revealed that the granulomatous and lymphoplasmacytic inflammatory infiltration of ocular tissues involves, in order of frequency, the conjunctiva, limbus, ciliary body, iris, cornea, sclera and iridocorneal angle, choroid, and the optic nerve sheath. 109 Anterior uveitis is perhaps the most common manifestation of ocular CanL, and regardless of its chronicity, is characterized by uveal and corneal edema, miosis, fibrin formation in the anterior chamber, and multiple nodules within the iris stroma (Fig.…”
Section: General Pathomechanismsmentioning
confidence: 99%
“…5). 57,110 Posterior uveitis, usually escorting anterior uveitis, is less commonly diagnosed. Multifocal chorioretinitis is consistent with small hyperreflective foci, retinal detachment, and hemorrhage in the tapetal fundus.…”
Section: General Pathomechanismsmentioning
confidence: 99%
“…These lesions might be the result of direct ocular parasitism but immune-mediated mechanisms have also been reported (KOUTINAS et al, 1999). Some investigators found that ocular disease can be uni-or bilateral and even cause more than one alteration in the same eye (PEÑA et al, 2000;BRITO, 2004). Studies have shown that both segments of the eye might be affected, but that lesions predominate in the anterior segment (MOLLEDA et al, 1993;BRITO, 2004;BRITO et al, 2004).…”
Section: Introductionmentioning
confidence: 99%