Ocular biometry in dense cataracts: Comparison of partial-coherence interferometry, swept-source optical coherence tomography and immersion ultrasound

Abstract

Purpose: To assess the axial length (AL) measurement failure rate using partial-coherence interferometry (PCI) and swept-source optical coherence tomography (SS-OCT) in dense cataracts. As a secondary outcome, the SS-OCT biometry was compared to immersion ultrasound. Methods: This is a prospective cross-sectional and comparative study. Seventy eyes from 70 patients with dense cataracts were enrolled in this study. Dense cataract was defined according to the Lens Opacities Classification System III (LOCS III) scores equal to or more than NO4, NC4, C4, and P3. The failure rate of AL measurement was evaluated using PCI and SS-OCT. Anterior chamber depth (ACD), lens thickness (LT), and AL measurements obtained by SS-OCT were compared with IUS. Results: AL measurement failure rate with PCI was 68.57% and 21.43% with SS-OCT ( P = 0.007). AL measurement was achieved in 69.23% of NO4, 66.6% of P3, and 15.3% of mixed cataracts using PCI, while SS-OCT was achieved in 100% of NO4, NO5, P3, and P5 and 76.9% of mixed cataracts. Cortical cataracts alone did not influence AL measurement. Biometric data of ACD, LT, and AL were statistically different comparing US and SS-OCT with a good correlation of AL. Conclusion: SS-OCT significantly improves the rate of successful AL measurements when compared to PCI in dense cataracts. The LOCS III clinical cut-off for the use of SS-OCT ocular biometry may well be up to P4 and NO5.

Comparison of anterior segment parameters of patients with myopia measured using 2 swept-source optical coherent biometry devices

“…Since 1999, optical biometry has emerged as the conventional method for measuring AXL owing to its non-invasiveness and comparable results to those obtained through ultrasound biometry. [11,12] Until 2009, the intraocular lens (IOL) Master 500, based on partial coherence interferometry, was the only device to measure AXL optically. [13] In recent years, the IOL Master 700 biometer has been introduced and widely adopted.…”

Comparison of axial length and anterior segment parameters of patients with myopia measured using 2 fourier-domain optical coherent biometry devices

“…Since 1999, optical biometry has emerged as the conventional method for measuring AXL owing to its non-invasiveness and comparable results to those obtained through ultrasound biometry [ 11 , 12 ]. Until 2009, the intraocular lens (IOL) Master 500, based on partial coherence interferometry, was the only device to measure AXL optically [ 13 ].…”

Comment on: Comparison of the ocular ultrasonic and optical biometry devices in different quality measurements

“…Future research could investigate how various cataract types influence the reliability and agreement of measurements. 3 …”

“…The density of cataracts can vary among patients and might affect the quality of measurements differently investigating the relationship between cataract density and measurement reliability could be a valuable research direction. 3 …”