PURPOSE. To determine the association between ocular dominance and spherical/astigmatic anisometropia, age, and sex in hyperopic subjects.METHODS. The medical records of 1274 hyperopic refractive surgery candidates were filtered. Ocular dominance was assessed with the hole-in-the-card test. Refractive error (manifest and cycloplegic) was measured in each subject and correlated to ocular dominance. Only subjects with corrected distance visual acuity of >20/22 in each eye were enrolled, to exclude amblyopia. Associations between ocular dominance and refractive state were analyzed by means of t-test, v 2 test, Spearman correlation, and multivariate logistic regression analysis.RESULTS. Right and left eye ocular dominance was noted in 57.4 and 40.5% of the individuals. Nondominant eyes were more hyperopic (2.6 6 1.27 diopters [D] vs. 2.35 6 1.16 D; P < 0.001) and more astigmatic (À1.3 6 1.3 D vs. À1.2 6 1.2 D; P ¼ 0.003) compared to dominant eyes. For spherical equivalent (SE) anisometropia of >2.5 D (n ¼ 21), the nondominant eye was more hyperopic in 95.2% (SE 4.7 6 1.4 D) compared to 4.8% (1.8 6 0.94 D; P < 0.001) for the dominant eye being more hyperopic. For astigmatic anisometropia of >2.5 D (n ¼ 27), the nondominant eye was more astigmatic in 89% (mean astigmatism À3.8 6 1.1 D) compared to 11.1% (À1.4 6 1.4 D; P < 0.001) for the dominant eye being more astigmatic.CONCLUSIONS. The present study is the first to show that the nondominant eye has a greater degree of hyperopia and astigmatism than the dominant eye in hyperopic subjects. The prevalence of the nondominant eye being more hyperopic and more astigmatic increases with increasing anisometropia. (Invest Ophthalmol Vis Sci. 2012;53:5362-5369) DOI: 10.1167/iovs.11-8781 F unctional lateralization occurs in the paired organs of the body, such as hands, legs, eyes, and cerebral hemispheres; but the exact mechanisms resulting in lateralization as well as the strength and quality of lateralization remain obscure.In 1903, Rosenbach claimed that most people have a dominant eye, even though each of their two eyes in isolation may provide equal vision and, in unequal vision, the dominant eye is not always the eye with better visual acuity. In general, ocular dominance is defined as the tendency to prefer visual input from one eye over the other 2,3 and may be further characterized as a status whereby one of the eyes commonly dominates or leads the other eye, both in fixation and attention and in perceptive function. 4 Eye dominance, which is commonly determined with the hole-in-the-card test, provides the foundation for a range of clinical decisions, including contact lens wear, 5,6 cataract surgery, 7,8 and monovision presbyopic treatment, 9-11 and is thought to be important in the control of reading.
12The role of ocular dominance in surgically induced monovision can be assessed by looking at success rates and patient satisfaction after monovision refractive surgery. [13][14][15] This clinical practice is based on the assumption that it will be easier to suppress b...