Ocular hemodynamics in pseudoexfoliation syndrome and pseudoexfoliation glaucoma

Ischemic Changes in a Case of Unilateral Pseudoexfoliation Syndrome

“…We have previously shown that in unilateral PXS, the affected side has significantly higher mean ophthalmic artery RI (mean ± SD, 95% CI; 0.74 ± 0.04 cm/s, 0.72-0.75) compared to age-sex matched controls (0.69 ± 0.07 cm/s, 0.66-0.72; p=0.009) [5]. Similar results were obtained by Yüksel et al [4] We have suggested a value of 0.72 for RI to be the cut-off value for differentiation of PXS. The case in discussion had a left ophthalmic artery RI of 0.88 which is far above what we had reported for the unilateral PXS [5].…”

“…Accumulation of pseudoexfoliative material in iridial vessel walls is associated with increased permeability, narrowing, and finally obstruction [2]. Increased ophthalmic artery resistivity index (RI) in pseudoxfoliation have been reported by two independent studies [4,5]. Saatçi et al found presence of pseudoexfoliative material as a likely risk factor for retinal vein occlusion [6].…”

Análise da correlação entre síndrome de pseudo-exfoliação e aneurisma de aorta abdominal

“…A SPEX foi definida como a presença de material pseudoexfoliativo sobre a cápsula anterior do cristalino ou próximo à pupila, bem como a presença de três dos quatro critérios a seguir: defeitos de transiluminação na porção pupilar da íris, atrofia de liseré, presença da linha de Sampaolesi à gonioscopia e zonas de descontinuidade óptica, pigmentadas, no humor aquoso à midríase medicamentosa (13) . Em relação aos achados oculares, também não houve diferença significante entre as médias da acuidade visual, pressão intra-ocular e diâmetro da escavação do disco óptico entre os dois grupos.…”

Cerebral haemodynamics in patients with pseudoexfoliation glaucoma

“…6 It has been shown that pseudoexfoliation syndrome is associated with an alteration in the retrobulbar haemodynamics. 7 This alteration is more prominent in pseudoexfoliation glaucoma. 7 A recent study has shown that total cerebral blood perfusion is reduced and the cerebrovascular responses to hyperoxia are abnormal in open-angle glaucoma patients compared with controls.…”

“…7 This alteration is more prominent in pseudoexfoliation glaucoma. 7 A recent study has shown that total cerebral blood perfusion is reduced and the cerebrovascular responses to hyperoxia are abnormal in open-angle glaucoma patients compared with controls. 8 Pseudoexfoliation is a systemic disorder [1][2][3] and has an association with the vascular diseases, including angina, acute myocardial infarction, or stroke.…”