Ocular involvement in tumoral calcinosis

Abstract

We report a 32-year-old male who presented with blurring of vision in the right eye since 1.5 years. He had history of swelling over the extensor surfaces of large joints which were migratory in nature. Few of them spontaneously subsided following suppuration of chalky white discharges except over the gluteal region. Ophthalmological examination revealed visual acuity of counting fingers (CF) at 1 m in the right eye and perilimbal conjunctival calcific deposits and retinal angiod streaks in both eyes. There was choroidal neovascular membrane with subretinal hemorrhage in right eye, confirmed by fundus fluorescein angiography (FFA) and optical coherence tomography (OCT). B scan ultrasonography and simultaneous vector A scan detected calcification of the subretinal neovascular membrane and the adjoining sclera.

A 23-year-old patient with secondary tumoral calcinosis: Regression after subtotal parathyroidectomy

“…Patients often complain about localized swelling and reduced mobility around the involved joints. Furthermore, calcifying organ manifestation is typically found in eyes [6] , as was seen as well in our patient.…”

“…The limitation in FGF23 activity induces increased renal tubular reabsorption of phosphate and thus hyperphosphatemia. The result is typically calcification of the entire body [5] , [6] .…”

Choroidal Neovascular Membrane Association with Tumoral Calcinosis, a Case Report

“…It has been linked with certain ophthalmic presentations that are associated with calcification such as calcific lid lesions of the eyelid, Band keratopathy, Conjunctival calcific lesions, angioid streaks and choroidal neovascular membranes [6][7][8][9][10][11][12][13][14]. To our knowledge this is the Third published case in the English literature that describes the involvement of Tumoral Calcinosis with choriodal neovascular membrane in the retina.…”