Ocular manifestations and complications in a cohort of Behçet’s disease patients in a tertiary hospital

Refaat, Maged; Said, Azza Mohamed Ahmed; Ebeid, Ahmed Abdelmonsef; Elmazly, Ahmed Yehia; Sheha, Dina Sayed

doi:10.1016/j.ejr.2020.07.007

Cited by 3 publications

(3 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This agreed with Refaat et al, who stated that ocular complications were among the highest records in their study. 18 This agreed with previous reports of Piga et al and Elgengehy et al who found that mucocutaneous damage and ocular damage were the most common. 8,9 On the other hand, Suppiah et al stated that ENT and neuropsychiatric systems had the most frequent organ damage as determined by VDI.…”

Section: Discussionsupporting

confidence: 93%

“…In this work, the most frequent organ systems damage, as determined by the 3 indices, were the ocular and mucocutaneous systems. This agreed with Refaat et al, who stated that ocular complications were among the highest records in their study 18 . This agreed with previous reports of Piga et al and Elgengehy et al who found that mucocutaneous damage and ocular damage were the most common 8,9 .…”

Section: Discussionsupporting

confidence: 92%

See 1 more Smart Citation

Damage accrual in Behçet disease: Behçet's Syndrome Overall Damage Index (BODI) versus Behçet's Disease Damage Index (BDI)

et al. 2023

View full text Add to dashboard Cite

Objectives To assess the validity of Behçet's Syndrome Overall Damage Index (BODI) and Behçet's Disease Damage Index (BDI) as tools for the detection of damage accrual in Behçet's patients compared to Vasculitis Damage Index (VDI). Also, to evaluate the correlation and the interclass correlation among the 3 indices to find out their consistency. Method A prospective cohort study was carried out on 102 adult Behçet's disease (BD) patients who were diagnosed according to the International Study Group criteria for BD. Disease severity and organ damage were assessed for each patient by VDI, BDI and BODI at baseline and 1‐year follow‐up visits. Damage accrual for each index was defined when there was an increase of at least 1 point (∆ ≥ 1) among the baseline and the follow‐up visits. Results Correlations among the 3 indices were significant, with (r = 0.835, P < 0.001) between VDI and BODI, (r = 0.835, P < 0.001) between VDI and BDI, and (r = 0.844, P < 0.001) between BODI and BDI scores. A highly significant positive correlation existed between the 3 indices and age and disease duration. In contrast, the correlation with the BD Current Activity Form was non‐significant, which indicates good discriminative validity of the 3 indices. Neuropsychiatric and ocular systems showed a strong interclass correlation among the 3 indices. Regarding detecting damage accrual, BDI was more sensitive than BODI and showed more agreement with VDI. Conclusion BD damage indices, VDI, BODI and BDI, had good convergent and discriminative validity for the assessment of BD damage. BDI had more sensitivity than BODI to the detection of damage accrual.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 92%

Damage accrual in Behçet disease: Behçet's Syndrome Overall Damage Index (BODI) versus Behçet's Disease Damage Index (BDI)

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Behçet's disease (BD) is a chronic multisystemic vasculitis of unknown origin with unpredictable exacerbations and remissions, which is more prevalent in Turkey, Iran, Japan, and Korea (1). It is accompanied by recurrent mucocutaneous lesions, uveitis, arthritis, and presentations involving the skin, central nervous system, and gastrointestinal system.…”

Section: Introductionmentioning

confidence: 99%

Salivary Levels of Human Neutrophil Peptide (HNP) 1-3 in Patients with Recurrent Aphthous Stomatitis and Behçet’s Disease: A Cross-sectional Study in Iran

Saffari,

Mirfeizi,

Gholamalizadeh

et al. 2024

Journal of Kerman University of Medical Sciences

View full text Add to dashboard Cite

Background: Recurrent oral ulcers are the most common complaint of patients with Behçet’s disease (BD) and recurrent aphthous stomatitis (RAS). Enhanced innate immune response and neutrophilic activity might be a possible etiopathogenesis of BD. This study aimed to determine the significance of salivary human neutrophil peptide (HNP 1-3) in BD and RAS patients and detect their correlation with different clinical presentations, disease activity, and characteristics of oral ulcers. Methods: This cross-sectional study included 25 BD patients and 25 RAS patients as well as 25 healthy participants. Five cubic centimeters of unstimulated saliva was collected and levels of HNP 1-3 were measured by ELISA. Other data were obtained through interviews, examinations, and reviews of medical records. Finally, data analysis was performed using SPSS 25.0 software. Results: Salivary HNP 1-3 levels were not significantly different between the study groups (P=0.282). Duration of oral ulcers did not correlate with HNP 1-3 levels in RAS and BD patients (P > 0.05). Also, BD patients with involvements other than oral ulcers were not found to have different levels of HNP 1-3 compared to those who did not manifest these conditions. Conclusion: The validity of HNP 1-3 to be used as a probable biological marker for evaluation, diagnosis, and estimation of disease activity in patients with BD and RAS is still questionable according to our results.

show abstract

Pattern of uveitis in Behçet’s disease patients from a highly specialized university hospital-based tertiary care eye unit

Elzanaty,

Wassef,

Seif

et al. 2024

The Egyptian Rheumatologist

View full text Add to dashboard Cite

Ocular manifestations and complications in a cohort of Behçet’s disease patients in a tertiary hospital

Cited by 3 publications

References 26 publications

Damage accrual in Behçet disease: Behçet's Syndrome Overall Damage Index (BODI) versus Behçet's Disease Damage Index (BDI)

Damage accrual in Behçet disease: Behçet's Syndrome Overall Damage Index (BODI) versus Behçet's Disease Damage Index (BDI)

Salivary Levels of Human Neutrophil Peptide (HNP) 1-3 in Patients with Recurrent Aphthous Stomatitis and Behçet’s Disease: A Cross-sectional Study in Iran

Pattern of uveitis in Behçet’s disease patients from a highly specialized university hospital-based tertiary care eye unit

Contact Info

Product

Resources

About