Ocular Manifestations of Herpes Simplex Virus in the Pediatric Population

Smith, Logan M.; Ismail, Omar M; Mojica, Gioconda

doi:10.1097/iio.0000000000000394

Cited by 2 publications

(3 citation statements)

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“…The clinical presentation of uveitis can provide diagnostic clues to facilitate the identification of the relevant disease entity underpinning the ongoing inflammatory process in the eye. Table 2 [ 2 , 13 , 19 , 20 ] and Table 3 [ 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 ] list the symptoms characteristic of uveitis for each disease entity, categorized by infectious and non-infectious agents.…”

Section: Resultsmentioning

confidence: 99%

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Diagnosis and Treatment of Uveitis in Children: A Summary of the Latest Data from a 5-Year Literature Review (2018–2023)

Modrzejewska,

Zdanowska

2024

JCM

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Pediatric uveitis has a low incidence. It is very diverse in its presentation and is often the first sign of a severe systemic disease. The pediatric population poses a special therapeutic and diagnostic challenge due to the potentially adverse effects of therapeutic agents on the young body and difficult cooperation with the patient during the examination, as well as the increased risk of complications that can lead to severe disability. The most commonly diagnosed type of uveitis is non-infectious, with first-line therapy consisting of systemic corticosteroids followed by disease-modifying drugs (methotrexate (MTX), mycophenolate mofetil (MMF), and cyclosporin A (CsA)). In severe, refractory cases, biologic therapy is used. The authors reviewed the current literature on the etiology, diagnostic tools, and treatment of uveitis in the pediatric population covering the years 2018–2023, presenting current methods of modern diagnosis and treatment. The reason for writing this article was the need to update the knowledge on uveitis, driven by the increasing prevalence of autoimmune uveitis in the pediatric population. This trend presents significant challenges in diagnosing and treating the disease, as well as managing its complications. Correctly identifying the pathogenetic factor of uveitis can facilitate the diagnosis of the systemic disease underlying the ocular infection and enable the timely implementation of systemic treatment. Furthermore, the emergence of new diagnostic methods necessitates a revision and update of ophthalmic knowledge, essential for both ophthalmologists and other specialists involved in the treatment of uveitis.

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Section: Resultsmentioning

confidence: 99%

“…Unilateral uveitis and/or keratitis, inflammatory cells in the anterior chamber, atrophy of the iris, increase in intraocular pressure [19].…”

Section: Herpes Virusesmentioning

confidence: 99%

Diagnosis and Treatment of Uveitis in Children: A Summary of the Latest Data from a 5-Year Literature Review (2018–2023)

Modrzejewska,

Zdanowska

2024

JCM

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“…В ряде случае вирус герпеса поражает глаза, вызывая герпетический кератит [8,17,18] и органы слуха [19]. Кератит, вызванный вирусом простого герпеса первого типа, является основной причиной слепоты в результате повреждения роговицы [17,20]. Также HSV-1 может вызвать многоформную эритему [21] и пневмонит [22].…”

Section: материалы и методыunclassified

The role of Herpes Simplex Virus type 1 in oral diseases in children

Ivanovskii

Antonova

Molokova

2022

jour

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Relevance. Herpes virus infections are the most common and poorly controllable viral infections. There are many difficulties in herpetic lesion verification and treatment in dental practice.Purpose. The study aimed to present the results of a foreign publication investigation on the role of herpes simplex virus type 1 in the development of oral diseases in children.Material and methods. Foreign scientific articles about the oral HSV-1 infections published from 2018 to 2022 formed the basis for the study. The study searched the publications on PubMed and Google Scholar bases.Results. The article presents the newest data on the prevalence, clinical characteristics and diagnosis of oral HSV infection in children. Primary herpetic gingivostomatitis (PHGS), chronic recurrent herpetic gingivostomatitis, chronic recurrent herpes labialis are the main clinical presentations of herpes infection diagnosed in a dental practice. Primary herpetic gingivostomatitis is very common in children aged six months to fve years and occurs in newborns from 2 to 43 days of life. Modern virology success can improve diagnosis and treatment of oral herpetic lesions.Conclusion. Primary herpetic gingivostomatitis is an acute infectious disease that requires the joint attention of a general practitioner and a dentist to ensure comprehensive treatment.

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Ocular Manifestations of Herpes Simplex Virus in the Pediatric Population

Cited by 2 publications

References 48 publications

Diagnosis and Treatment of Uveitis in Children: A Summary of the Latest Data from a 5-Year Literature Review (2018–2023)

Diagnosis and Treatment of Uveitis in Children: A Summary of the Latest Data from a 5-Year Literature Review (2018–2023)

The role of Herpes Simplex Virus type 1 in oral diseases in children

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