Ocular Onchocerciasis in the Yanomami Communities from Brazilian Amazon: Effects on Intraocular Pressure

Herzog-Neto, Guilherme; Jaegger, Karen; Nascimento, Érika S; Marchon-Silva, Verônica; Banic, Dalma Maria; Maia-Herzog, Marilza

doi:10.4269/ajtmh.13-0357

Cited by 8 publications

(9 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, in older infections, ocular onchocerciasis can also be observed, where microfilariae invade the ocular structures by migration and contiguity, compromising visual capacity due to microfilariae death, in the anterior chamber of the eye, causing alterations such as eyelid edema, iritis, punctate keratitis, scleroceretitis, chorioretinitis and amaurosis. The prevalence and intensity of microfilaremia increases significantly with exposure to the vector and, consequently, patient age, although no association was found with sex and intraocular pressure of the affected indigenous people [ 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

A new methodology for sampling blackflies for the entomological surveillance of onchocerciasis in Brazil

et al. 2017

Self Cite

View full text Add to dashboard Cite

The effectiveness of the MosqTent® trap was evaluated in endemic area to onchocerciasis in Brazil. This study seeks to provide subsidies for the monitoring of the onchocerciasis transmission in the country. The study was carried out at the Homoxi and Thirei villages, located in the Yanomami Indigenous Land, in the state of Roraima. This area presents hyperendemicity, high blackflies densities, large population migrations and mining activities. The Homoxi and Thirei villages are assisted by the Brazilian Ministry of Health. To conduct the present study, the village leader, health leaders and the Brazilian Ethics Committee were consulted. Blackflies captures were carried out simultaneously at the Homoxi and Thirei, using systematized methods to allow for comparisons between the traditional Human Landing Catch (HLC) and HLC protected by the MosqTent®. The female blackflies were captured at two equidistant capture stations per locality, by two collectors per station, for five consecutive days. Individuals captured by interval/station/day were counted, identified and maintained at -20°C. The underlying probability distributions and the differences between the methods for the independent sample data were verified in a comparative statistical analysis between the use of the MosqTent® and the HLC. A total of 10,855 antropophilic blackflies were captured by both methodologies. A total of 7,367 (67.87%) blackflies belonging to seven species were captured by MosqTent® —Simulium incrustatum s.l (99.06%); S. guianense s.l (0.74%), S. oyapockense s.l (0.01%), S. exiguum (0.10%), S. metallicum (0.05%), S. ochraceum (0.03%) and S. minusculum s.l (0.01%). Moreover, 3,488 (32.14%) blackflies belonging to four species were captured by HLC—S. incrustatum s.l (98.33%); S. guianense s.l (1.38%), S. oyapockense s.l (0.26%) and S. metallicum (0.03%). The MosqTent® was more effective and efficient when compared to HLC. When comparing total blackflies captured/day, the MosqTent® was more efficient than HLC (p = 0.031) with a means of 799.4 blackflies/day versus 217.6 blackflies/day by HLC. The results demonstrated improved performance and high reliability of the MosqTent® compared to the traditional HLC method.

show abstract

Section: Introductionmentioning

confidence: 99%

A new methodology for sampling blackflies for the entomological surveillance of onchocerciasis in Brazil

et al. 2017

Self Cite

View full text Add to dashboard Cite

show abstract

“…The 85 included articles described 64 unique studies that examined a total of 79 598 unique indigenous participants in 24 countries during the past 28 years (Table 1). Considering that indigenous populations inhabit approximately 90 countries, this indicates that the burden of visual loss and eye disease in most indigenous peoples around the world has not been adequately investigated.…”

Section: Resultsmentioning

confidence: 99%

“…Late-stage trachoma, including trichiasis and corneal opacification, affected 8.3% of indigenous Australians in Central Australia and 8.0% of Tiquié people in Brazil. Only 3 studies described the prevalence of ocular onchocerciasis in indigenous populations, with 33.5% of Chachi Amerindians in Ecuador and 38.5% to 68.6% of Yanomami Indians in Brazil affected.…”

Section: Resultsmentioning

confidence: 99%

Prevalence and Causes of Visual Loss Among the Indigenous Peoples of the World

et al. 2018

View full text Add to dashboard Cite

IMPORTANCEStudies have documented a higher disease burden in indigenous compared with nonindigenous populations, but no global data on the epidemiology of visual loss in indigenous peoples are available. A systematic review of literature on visual loss in the world's indigenous populations could identify major gaps and inform interventions to reduce their burden of visual loss.OBJECTIVE To conduct a systematic review on the prevalence and causes of visual loss among the world's indigenous populations.EVIDENCE REVIEW A search of databases and alternative sources identified literature on the prevalence and causes of visual loss (visual impairment and blindness) and eye diseases in indigenous populations. Studies from January 1, 1990, through August 1, 2017, that included clinical eye examinations of indigenous participants and, where possible, compared findings with those of nonindigenous populations were included. Methodologic quality of studies was evaluated to reveal gaps in the literature.FINDINGS Limited data were available worldwide. A total of 85 articles described 64 unique studies from 24 countries that examined 79 598 unique indigenous participants. Nineteen studies reported comparator data on 42 085 nonindigenous individuals. The prevalence of visual loss was reported in 13 countries, with visual impairment ranging from 0.6% in indigenous Australian children to 48.5% in native Tibetans 50 years or older. Uncorrected refractive error was the main cause of visual impairment (21.0%-65.1%) in 5 of 6 studies that measured presenting visual acuity. Cataract was the main cause of visual impairment in all 6 studies measuring best-corrected acuity (25.4%-72.2%). Cataract was the leading cause of blindness in 13 studies (32.0%-79.2%), followed by uncorrected refractive error in 2 studies (33.0% and 35.8%).CONCLUSIONS AND RELEVANCE Most countries with indigenous peoples do not have data on the burden of visual loss in these populations. Although existing studies vary in methodologic quality and reliability, they suggest that most visual loss in indigenous populations is avoidable. Improvements in quality and frequency of research into the eye health of indigenous communities appear to be required, and coordinated eye care programs should be implemented to specifically target the indigenous peoples of the world.

show abstract

“…Nesse momento, surgem nódulos subcutâneos (oncocercomas), prurido, febre e exantemas cutâneos. Se as microfilárias migrarem para a região dos olhos podem causar redução da acuidade visual e até cegueira total (HERZOG-NETO et al, 2014).…”

Section: Oncocercoseunclassified