2021
DOI: 10.21203/rs.3.rs-146734/v1
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Ocular Surface Pathology in Patients Suffering From Mercury Intoxication Is Consistent With Neurogenic Dry Eye Disease

Abstract: Purpose: To report ocular surface pathology of patients with acute/subacute mercury intoxication.Methods: Male workers intoxicated with inorganic mercury were examined for dry eye (DE)-related symptoms. Examinations included Ocular Surface Disease Index questionnaire; tear osmolarity, tear break-up time (T-BUT) and production; mechanical and thermal corneal sensitivity; corneal nerve and dendritic cell density analysis; and analysis of 23 tear cytokines.Results: Most patients, 63.6%, had severe DE-related symp… Show more

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