Odontogenic fibromyxoma: A case report in myasthenia gravis patient and review of the literature

Genç, Bedriye Gizem Çelebioğlu; Orhan, Kaan

doi:10.1016/j.ijscr.2022.107306

Cited by 2 publications

(1 citation statement)

References 29 publications

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“…The appearance of synchronous or metachronous odontogenic myxofibromas, in patients affected by rare, clinical entities, which may be characterized by genetic predisposition, supports the notion of a possible genetic background underlying the manifestation of MF. In particular, MF with angiosarcoma, MF with tuberous sclerosis, and MF with myasthenia gravis are reported in the literature [ 1 , 19 , 20 ]. In summary, based on the aforementioned information on MFs, peripheral MFs located in the oral mucosal soft tissues are extremely rare.…”

Section: Discussionmentioning

confidence: 99%

Rare Case of Peripheral Myxofibroma of Anterior Maxillary Gingiva: A Diagnostic Challenge

Lillis,

Zisis,

Fotopoulos

et al. 2023

Cureus

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The myxofibroma (MF) constitutes an uncommon, non-malignant, odontogenic neoplasm with potential mesenchymal derivation. The occurrence rate of this particular tumor is estimated to be around 0.05 new cases per million individuals annually. MFs exhibit a higher incidence rate within the age range of 10 to 30 years. The prevalence of these tumors is higher among the female population, with a predominant localization in the mandible, specifically in the posterior region. A female patient, 66 years old, was referred to the Department of Oral Surgery, Surgical Implantology and Radiology, Thessaloniki, Greece, complaining of a tumorous lesion in the anterior area of the maxilla and mild pain. Clinically, a solid in palpation lobulated tumor, covered by normal coloured mucosa was observed at the left upper incisor. After the excisional biopsy, the microscopic appearance of abundant fibromyxoid stroma, in particular, myxoid stroma intermingled with collagenous tissue, covered by stratified squamous epithelium, suggested the diagnosis of peripheral myxofibroma. During a 2-year follow-up, no recurrence was referred. This case illustrates the necessity of proper differential diagnosis of every tumorous lesion of the gingiva and of using the histopathological examination.

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Section: Discussionmentioning

confidence: 99%

Rare Case of Peripheral Myxofibroma of Anterior Maxillary Gingiva: A Diagnostic Challenge

Lillis,

Zisis,

Fotopoulos

et al. 2023

Cureus

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Rare Hybrid Tumor of Odontogenic Fibromyxoma and Central Giant Cell Granuloma in Maxilla: First Reported Case

Pandey,

Bagul,

Talmohite

et al. 2023

Indian Journal of Dental Research

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Fibromyxoma is a locally aggressive rare benign tumor of mesenchymal origin with or without odontogenic epithelium. The etiology of this tumor remains unknown and it is responsible for approximately 3–8% of all cysts and tumors. Another locally destructive benign lesion is central giant cell granuloma (CGCG) which contains osteoclast-like multinucleated giant cells. CGCG accounts for about 7% of all benign jaw tumors, which usually affects younger females. A hybrid lesion with histologic features of both central fibromyxoma and CGCG has not been reported in the literature so far. In the present article, we report the first case of a hybrid tumor comprising odontogenic fibromyxoma with CGCG in a female along with a brief review of its clinical presentation, radiographic features, histological features, and management.

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Odontogenic fibromyxoma: A case report in myasthenia gravis patient and review of the literature

Cited by 2 publications

References 29 publications

Rare Case of Peripheral Myxofibroma of Anterior Maxillary Gingiva: A Diagnostic Challenge

Rare Case of Peripheral Myxofibroma of Anterior Maxillary Gingiva: A Diagnostic Challenge

Rare Hybrid Tumor of Odontogenic Fibromyxoma and Central Giant Cell Granuloma in Maxilla: First Reported Case

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