Odontogenic myxoma: Report of two cases

Abstract

Odontogenic tumors represents a broad spectrum of lesions ranging from benign to malignant to dental hamartomas all arising from odontogenic residues, that is, the odontogenic epithelium, ectomesenchyme with variable amounts of dental hard tissues formed in the same sequence as in normal tooth development. We report two cases of myxoma, which were misdiagnosed initially and latter, reported as odontogenic myxoma; and were treated by conservative surgical excision in one case and radical resection with hemimandibulectomy in the other case.

Odontogenic Myxoma of the Mandible

“…The tumor is not radiosensitive, and surgery is the treatment of choice. 2,4,6,8 The lack of a capsule and infiltrative growth pattern is responsible for high rate of recurrence when conservative enucleation and curettage are performed. Recurrence is minimized with extensive partial or total resection procedures.…”

“…The evidence for its odontogenic origin arises from its almost exclusive location in the tooth bearing areas of the jaws, its occasional association with missing or unerupted teeth, and the presence of odontogenic epithelium. 4,6 The odontogenic nature of the myxomas has been challenged by some authors because of the appearances, whilst consistent with odontogenic ectomesenchyme, could also represent a more primitive fibroblastic or undifferentiated tissue. 7 Most of the OMs reported were young adults affected mostly in their second and third decade of life with marked female predilection.…”

“…7 Most of the OMs reported were young adults affected mostly in their second and third decade of life with marked female predilection. 2,4,6,7 Clinically, OMs are slow growing, painless, and locally aggressive tumors. Since pain and hypoesthesia are not common, the lesions may reach a considerable size before patient perceives its existence and seeks treatment.…”

Odontogenic Myxoma –Report Of A Rare Case

“…[3,10] However possibility of occurrence in maxilla, mandibular incisive area and condylar region should not be neglected. [10] Odontogenic myxoma rarely crosses the midline.…”

“…[8] Odontogenic myxoma accounts for around 3-6% of all odontogenic tumours with a slightly higher frequency noted in America, Europe and Asia [3,10] It is more common in females of second and fourth [11] It is more common in posterior mandibular ramus region. [3,10] However possibility of occurrence in maxilla, mandibular incisive area and condylar region should not be neglected. [10] Odontogenic myxoma rarely crosses the midline.…”