Odontogenic tumors in Port Harcourt: South–South geopolitical zone of Nigeria

Abstract

Aim:A retrospective study of odontogenic tumors (OTs) in Port Harcourt was undertaken to establish its prevalence and compare with known data in the literature from Nigeria and elsewhere.Materials and Methods:All pathologically diagnosed OTs between 2008 and 2013 at the archives of the Department of Oral Pathology and Oral Biology of the University of Port Harcourt/University of Port Harcourt Teaching Hospital were retrospectively studied and classified according to the 2005 WHO classification of OTs and allied diseases. These were recorded into a computer and analyzed using Statistical Package for Social Sciences (SPSS 21.0, Inc., Chicago, IL, USA).Results:A total of sixty-three cases of OTs were recorded for the period under review. Fifty-two of these were cases of ameloblastoma (82.54%). This was followed by adenomatoid odontogenic tumour (AOT) 4 (6.35%) and odontogenic myxoma 3 (4.76%). Most lesions were seen within the second to fourth decades of life and mandible was most frequently affected.Conclusion:It is concluded that the pattern of occurrence of OTs in Port Harcourt followed a general pattern in Nigeria and other African countries but slightly differs from findings from other parts of the world.

Biological profile of ameloblastoma and its location in the jaw in 1246 Nigerians

“…This finding is in agreement with previous studies performed in a different part of Nigeria. 5,6,9,20,27 Peripheral ameloblastoma occurred in only 9 cases, accounting for 0.7% of all cases, which is low compared with the previous findings by Olaitan et al, 27 who reported 4 (1.3%) of 315 cases of ameloblastoma in the soft tissue in patients seen at the Ahmadu Bello University Hospital, Kaduna, Nigeria, with an incidence of 2% to 10%, as reported in the literature. 28,29 The average age at presentation of peripheral ameloblastoma was 44 years in this study, whereas the average age reported in the literature was 52 to 54 years.…”

“…[2][3][4] The prevalence rate could increase to 40% to 84% of odontogenic tumors when odontomas are not included or in centers where odontomas are not commonly diagnosed. 3,[5][6][7] Ameloblastoma has a high capacity to infiltrate between the trabeculae of cancellous bone, leaving cortical bone intact for some time. Thus, the tumor is usually present for some time before the patient presents with symptoms.…”

Odontogenic Myxoma: Systematic review and bias analysis

“…A total of 142 articles were eligible for full‐text evaluation. Subsequently to full‐text evaluation, 52 articles were included for qualitative analysis 6,13‐63 . Of those, 33 studies were a cross‐sectional and 19 were case series.…”

Cistos e tumores odontogênicos: estudo retrospectivo dos casos diagnosticados no período de 10 anos em um hospital no sul do Brasil

“…Outros TOs, incluindo cementoblastoma, fibroma ameloblástico, tumor odontogênico adenomatóide e o caso maligno de carcinoma ameloblástico, compreenderam somente cerca de 3% do total da amostra. Diferentes estudos demonstram uma baixa incidência de TOs, sendo que os tipos histológicos normalmente mais prevalentes são o odontoma e o ameloblastoma 11,14,18,24,27 , corroborando com os nossos achados. Os TOs malignos representaram 0,39% dentre todas as LOs avaliadas no presente estudo.…”

“…Os TOs podem variar desde proliferações hamartomatosas até neoplasias benignas ou malignas com potencial metastático 8,9 . Seu desenvolvimento pode ocorrer centralmente, no interior do osso, ou perifericamente, em regiões extra ósseas, e sua etiopatogenia ainda é incerta [9][10][11] . Os TOs são lesões relativamente raras, compreendendo cerca de 1% de todos os tumores que se desenvolvem nos ossos gnáticos [12][13][14] .…”