Odontogenic tumors: Review of 127 cases in Marathwada region of Maharashtra

Abstract

Introduction:Odontogenic tumors (OTs) are a group of heterogeneous lesions derived from epithelial or ectomesenchymal tissues or both, which are part of the tooth-forming apparatus. They range from hamartomatous or nonneoplastic tissue proliferations to malignant neoplasms with metastatic capacity. OTs are comparatively rare, comprising about 4.79% of all oral and maxillofacial biopsy specimens diagnosed. Several retrospective studies carried out in Africa, Asia, Europe and America, show that differences exist in the relative frequency of the various histologic types. Very few studies are reported among Asians, especially from the Indian subcontinent. Hence, the present study is designed to determine the frequency of the OTs and compare them with reports of various other part of the world.Study Design:A retrospective study was carried out with the ethical clearance and permission from the authority. The histopathology records from the Department of Oral Pathology and Microbiology, within the period from January 1992 to June 2012 were obtained. A total number of OTs were analyzed for age, gender, site of the tumor and histopathological type. The odontogenic keratocyst now considered as kerato cysticodontogenic tumor (KCOT) was also included in the present study.ResultsTotally, 2652 tissue specimens were received for histopathologic examination out of which 127 were OTs. All these reported cases were benign except two cases of malignancy. Among these male: female ratio of 1.04:1 with an overall mandible: maxilla ratio of 1.01:1. The most common benign odontogenic tumor was KCOT (44.9%). Ameloblastomas were the second most common benign tumors (35.43%), followed by odontome (7.08%) and adenomatoid odontogenic tumor (4.72%). Age distribution showed a peak occurrence of the odontogenic tumor in the fourth decade (31.49%).Conclusion:OTs are rare lesions in the studied population and are represented mainly by the KCOT, ameloblastoma and odontoma. Data from the reviewed cases have shown a possible geographic variation of OTs. With the introduction of the KCOT in the 2005 WHO classification, this neoplasm is now one of the most prevalent OT types.

Surgical management of a large calcifying epithelial odontogenic tumor in the maxilla: A case report

“…This tumor is more frequent in men [11,13,14] and usually develops in the posterior region of the mandible [11,12,14]. The lesions in the posterior maxilla region, as in the present case, represent less than 25% of all CEOTs [5,11]. Moreover, this tumor is more frequent in individuals between the third and sixth decade of life [12,14].…”

“…The odontogenic tumors represent between 2.3% and 4.7% of all lesions diagnosed in specific anatomic pathology services of the buccomaxillofacial complex [10,11]. The CEOT is also known as Pindborg tumor and is considered a rare pathological entity representing less than 2.5% of all odontogenic tumors [[11], [12], [13]], although a prevalence up to 15% has been found [14]. This tumor is more frequent in men [11,13,14] and usually develops in the posterior region of the mandible [11,12,14].…”

“…The CEOT is also known as Pindborg tumor and is considered a rare pathological entity representing less than 2.5% of all odontogenic tumors [[11], [12], [13]], although a prevalence up to 15% has been found [14]. This tumor is more frequent in men [11,13,14] and usually develops in the posterior region of the mandible [11,12,14]. The lesions in the posterior maxilla region, as in the present case, represent less than 25% of all CEOTs [5,11].…”

Ameloblastoma: Reconstruction using titanium plates adapted using stereolithographic models

“…[6] Ameloblastomas showed a high prevalence in the jaw (82.22%), in particular the posterior zone, in agreement with the case presented herein. [1] Ameloblastoma growth is aggressive but slow, so it can take many years until the patient decides to visit the dentist, which makes treatment more complicated due to the size of the tumor. [6]…”

“…Several retrospective studies in different continents report differences related to the frequency of the different histological types of tumors. [1]…”