Odors drive feeding through gustatory receptor neurons in<i>Drosophila</i>

Wei, Hongping; Lam, Ka Chung; Kazama, Hokto

doi:10.1101/2022.03.09.483541

Cited by 3 publications

(2 citation statements)

References 58 publications

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“…DAN’s odor responses mostly originate in the olfactory organs as they were largely diminished by removal of the antennae and maxillary palps (Figure S3). The remaining responses likely originate in the gustatory organs as gustatory receptor neurons also directly respond to odors (Wei et al, 2022). Odor responses increased with starvation and plateaued after 4 h (Figures S4), which coincides with the time when output from olfactory receptor neurons (ORNs) plateaus (Root et al, 2011).…”

Section: Resultsmentioning

confidence: 99%

Dopaminergic neurons dynamically update sensory values during navigation

Kato

Ohta

Okanoya

et al. 2022

Preprint

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Updating the value of sensory cues through experiences is a critical element of adaptive behavior. Although dopaminergic neurons (DANs) achieve this by driving associative learning, whether they contribute to assessment of sensory values outside the context of association remains largely unexplored. Here we show in Drosophila that DANs in the mushroom body encode the innate value of odors and constantly update the current value by inducing plasticity during olfactory navigation. Simulation of neuronal activity in a network based on the connectome data reproduced the characteristics of DAN responses, proposing a concrete circuit mechanism for computation. Notably, odors alone induced value- and dopamine-dependent changes in the activity of mushroom body output neurons, which store the current value of odors, as well as the behavior of flies steering in a virtual environment. Thus, the DAN circuit known for discrete, associative learning also continuously updates odor values during navigation in a non-associative manner.

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Section: Resultsmentioning

confidence: 99%

Dopaminergic neurons dynamically update sensory values during navigation

Kato

Ohta

Okanoya

et al. 2022

Preprint

Self Cite

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“…For example, the extensive connectome of the D. melanogaster larva revealed that the local interneurons of the antennal lobe receive input from unidentified non-olfactory sensory neurons, possibly gustatory in origin [101]. Recent work has also shown the converse, where gustatory receptor neurons respond to odors to regular proboscis extension reflex which serves as a readout for feeding behavior [102].…”

Section: Neuronal Substrates and Brain Centers Underlying Unimodal An...mentioning

confidence: 99%

Multimodal Information Processing and Associative Learning in the Insect Brain

Thiagarajan

Sachse

2022

Insects

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The study of sensory systems in insects has a long-spanning history of almost an entire century. Olfaction, vision, and gustation are thoroughly researched in several robust insect models and new discoveries are made every day on the more elusive thermo- and mechano-sensory systems. Few specialized senses such as hygro- and magneto-reception are also identified in some insects. In light of recent advancements in the scientific investigation of insect behavior, it is not only important to study sensory modalities individually, but also as a combination of multimodal inputs. This is of particular significance, as a combinatorial approach to study sensory behaviors mimics the real-time environment of an insect with a wide spectrum of information available to it. As a fascinating field that is recently gaining new insight, multimodal integration in insects serves as a fundamental basis to understand complex insect behaviors including, but not limited to navigation, foraging, learning, and memory. In this review, we have summarized various studies that investigated sensory integration across modalities, with emphasis on three insect models (honeybees, ants and flies), their behaviors, and the corresponding neuronal underpinnings.

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What are olfaction and gustation, and do all animals have them?

Derby,

Caprio

2024

Chemical Senses

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Different animals have distinctive anatomical and physiological properties to their chemical senses that enhance detection and discrimination of relevant chemical cues. Humans and other vertebrates are recognized as having two main chemical senses, olfaction and gustation, distinguished from each other by their evolutionarily conserved neuroanatomical organization. This distinction between olfaction and gustation in vertebrates is not based on the medium in which they live because the most ancestral and numerous vertebrates, the fishes, live in an aquatic habitat and thus both olfaction and gustation occur in water and both can be of high sensitivity. The terms olfaction and gustation have also often been applied to the invertebrates, though not based on homology. Consequently, any similarities between olfaction and gustation in the vertebrates and invertebrates have resulted from convergent adaptations or shared constraints during evolution. The untidiness of assigning olfaction and gustation to invertebrates has led some to recommend abandoning the use of these terms and instead unifying them and others into a single category – chemical sense. In our essay, we compare the nature of the chemical senses of diverse animal types and consider their designation as olfaction, oral gustation, extra-oral gustation, or simply chemoreception. Properties that we have found useful in categorizing chemical senses of vertebrates and invertebrates include the nature of peripheral sensory cells, organization of the neuropil in the processing centers, molecular receptor specificity and function.

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Odors drive feeding through gustatory receptor neurons inDrosophila

Cited by 3 publications

References 58 publications

Dopaminergic neurons dynamically update sensory values during navigation

Dopaminergic neurons dynamically update sensory values during navigation

Multimodal Information Processing and Associative Learning in the Insect Brain

What are olfaction and gustation, and do all animals have them?

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