Oesophageal acid-peptic strictures in the histamine H2 receptor antagonist and proton pump inhibitor era

Nayyar, Anil K.; Royston, Christine; Bardhan, Karna Dev

doi:10.1016/s1590-8658(03)00021-5

Cited by 22 publications

(19 citation statements)

References 26 publications

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“…The results of dilations were somehow inconsistent with those of Barbezat et al [28] , namely the re-dilation rate in this study was interestingly smaller in patients treated with H 2 RA (2.6/patient) compared with those treated with PPI (4.1/patient) [29] .…”

Section: Acid-suppressive Therapycontrasting

confidence: 99%

“…In an observational study by Nayyar et al [29] , 156 patients with esophageal stricture were followed-up for longer than 5 years. The results of dilations were somehow inconsistent with those of Barbezat et al [28] , namely the re-dilation rate in this study was interestingly smaller in patients treated with H 2 RA (2.6/patient) compared with those treated with PPI (4.1/patient) [29] .…”

Section: Acid-suppressive Therapymentioning

confidence: 99%

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Peptic Esophageal Stricture: Medical Treatment

Pregun

Hritz

Tulassay

et al. 2009

Dig Dis

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Peptic esophageal stricture as a consequence of gastroesophageal reflux disease is the most frequent among benign esophageal strictures. The incidence is low and has been decreasing since the 1990s with a parallel increase in proton pump inhibitor use. Dysphagia is a common symptom: accurate diagnostic procedures (barium esophagogram, upper endoscopy with biopsies) have to be performed to exclude malignant causes first. Medical (acid-suppressive) therapy, endoscopic dilation and surgical intervention are the main therapeutic options. Based on the results of randomized and observational studies evaluating the effect of acid-suppressive therapy on peptic stricture outcome, healing the coexistent esophagitis seems to be essential. Effective acid-suppressive therapy with proton pump inhibitors may reduce the need for repeated dilations and provide symptom relief and better clinical outcome. In refractory strictures, local steroid injection is likely beneficial.

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Section: Acid-suppressive Therapycontrasting

confidence: 99%

Section: Acid-suppressive Therapymentioning

confidence: 99%

Peptic Esophageal Stricture: Medical Treatment

Pregun

Hritz

Tulassay

et al. 2009

Dig Dis

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“…[14][15][16][17][18][19][20] Endoscopic dilation of PES is a safe and effective procedure in children. Three types of dilators are currently in use.…”

Section: Discussionmentioning

confidence: 99%

Peptic oesophageal stricture in children: Management problems

Zouari¹,

Kamoun²,

Bouthour³

et al. 2014

Afr J Paediatr Surg

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“…[17][18][19][20] The inability of total healing of the coexistent esophagitis is a predictive factor for the poor response to endoscopic dilatation. 19 There is a high rate of recurrence of erosive or ulcerating peptic esophagitis after discontinuation of acid-suppressive treatment even with documented esophageal healing.…”

Section: Methodsmentioning

confidence: 99%

“…19 There is a high rate of recurrence of erosive or ulcerating peptic esophagitis after discontinuation of acid-suppressive treatment even with documented esophageal healing. [17][18][19][20][21] Nevertheless, it is common knowledge that fundoplication in the pediatric population has significant rates of failure, and that the child may have to remain under clinical and endoscopic treatment after the procedure. 18,22 The efficacy and safety of omeprazole, combined with endoscopic treatment, defined a new pattern for the treatment of children with complicated reflux esophagitis, which should be the treatment of choice, reserving surgical treatment for refractory cases.…”

Section: Methodsmentioning

confidence: 99%

Tratamento das estenoses esofágicas por dilatação endoscópica em crianças e adolescentes

Bittencourt¹,

Carvalho²,

Ferreira³

et al. 2006

J. Pediatr. (Rio J.)

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Objective: To assess the causes of esophageal stricture in pediatric patients and their response to endoscopic dilatation.Methods: Retrospective analysis of clinical and endoscopic data obtained from children and adolescents with esophageal stricture submitted to endoscopic dilatation between July 1993 and January 2003.Results: A total of 125 patients aged between 1 month and 16 years were included in the study. Among the types of stenosis, postoperative (43.2%), corrosive (27.2%) and peptic (21.6%) strictures were the most prevalent. Those patients with corrosive esophageal stricture needed more dilatation sessions. Five cases of esophageal perforation and one case of hemorrhage occurred due to complications during the procedure. Good response to endoscopic treatment was described in 74.4% of cases, but better results were obtained from patients with peptic esophageal stricture.Conclusions: Endoscopic treatment of esophageal strictures in children and adolescents yields good results and has a low rate of complications. Corrosive esophageal strictures have a higher morbidity and require more dilatation sessions.

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Oesophageal acid-peptic strictures in the histamine H2 receptor antagonist and proton pump inhibitor era

Cited by 22 publications

References 26 publications

Peptic Esophageal Stricture: Medical Treatment

Peptic Esophageal Stricture: Medical Treatment

Peptic oesophageal stricture in children: Management problems

Tratamento das estenoses esofágicas por dilatação endoscópica em crianças e adolescentes

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