Oesophageal cancer

Abstract

SummaryOesophageal cancer is a clinically challenging disease requiring a multidisciplinary approach.The extensive treatment may be associated with serious limitations in health-related quality of life and yet still a poor prognosis. Recent decades have witnessed a gradual improvement in prognosis in many countries. Endoscopic procedures have increasingly been used in the treatment of premalignant and early oesophageal tumours. Neoadjuvant therapy with chemotherapy or chemoradiotherapy has supplemented surgery as standard treatment of locally advanced oesophageal cancer. Surgery has become more standardised and centralised. There are several therapeutic alternatives for palliative treatment. This review aims to provide insights into the current clinical management, on-going controversies and future needs in oesophageal cancer.3

Clinical outcomes of video-assisted thoracoscopic surgery esophagectomy for esophageal cancer: a propensity score-matched analysis

“…The number of harvested lymph nodes was not significantly different (31 vs. 33, P=0.198) between the two groups, satisfying the requirements for the Worldwide Esophageal Cancer Collaboration data (12,13). Lagerson and colleagues suggested that a higher number of harvested lymph nodes provided better survival in esophageal cancer (2). Many surgeons believe that MIE is inappropriate in obtaining adequate lymph node harvesting and that insufficient lymph node harvesting leads to a lower incidence of pulmonary complication outcomes.…”

“…However, esophagectomy is still the mainstay treatment modality for resectable esophageal cancer, despite its high operative mortality and morbidity (2). Moreover, pulmonary complications, such as pneumonia, ARDS, and other respiratory complications, despite recent progress in anesthetic procedures and postoperative care, still remain to be the most adverse events following esophagectomy (3).…”

“…Despite recent advancements in multidisciplinary approaches, surgical resection is still the mainstay treatment for potentially resectable esophageal cancer (2). However, esophageal cancer surgery remains to have high postoperative morbidity and mortality.…”

“…However, esophageal cancer surgery remains to have high postoperative morbidity and mortality. This is most likely associated with extensive and aggressive surgical procedures (2)(3)(4)(5).…”

18F‐Fluorodeoxyglucose positron emission tomography can be used to determine the indication for endoscopic resection of superficial esophageal cancer

“…Esophageal cancer is one of the most aggressive cancers of the digestive tract 1. Historically, the most important therapy has been esophagectomy with extended lymphadenectomy 2, 3.…”