Off-pump coronary artery bypass grafting in patients with left main disease: is it really safe?

Khabbaz, Ziad

doi:10.1016/j.ejcts.2010.04.005

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…Left main coronary artery stenosis > 70% is one of the risk factors for operative death in patients undergoing CABG, although there is controversy in identifying highrisk patients [9]. Calcified ascending aorta and aortic root are more likely to occur in patients with LMD, which may lead to severe ischemia, and intractable ventricular fibrillation in case of displacement of heart during OPCABG [10]. The most severe complication of OPCABG is hemodynamic compromise or collapse, which usually leads to conversion to CPB [11].…”

Section: Discussionmentioning

confidence: 99%

Prophylactic intra-aortic balloon pump in patients with left main disease undergoing off-pump coronary artery bypass grafting

Zheng

Hua

Zhang

et al. 2020

BMC Cardiovasc Disord

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Background: Preventive intra-aortic balloon pump (IABP) for high-risk patients with stable hemodynamics is controversial, and its definition of high-risk is still unclear. This study aimed to investigate the effect of prophylactic IABP on the early outcome of left main disease (LMD) patients receiving off-pump coronary artery bypass grafting (OPCABG) with stable hemodynamics. Methods: From January 2013 to April 2020, 257 consecutive patients who underwent OPCABG through sternotomy were enrolled in this study. All LMD patients (greater than 70%) had stable hemodynamics (BP>100 mmHg without vasoconstrictor substance infusion). Early outcomes of 125 patients with prophylactic IABP (IABP group) and 132 patients without IABP (Control group) were compared in this study. Results: IABP did not show favorable effect on the conversion to CPB (RR 0.63, 95%CI 0.05-7.89, P = 0.7211), perioperative MI (RR 0.69, 95%CI 0.22-2.12, P = 0.5163), mortality (RR 0.65, 95%CI 0.04-10.25, P = 0.7608) or the composite end of the conversion, MI and mortality (RR 0.63, 95%CI 0.23-1.74, P = 0.3747). There was greater incidence of prolonged ventilation in IABP after adjustment (RR2.16, 95%CI 1.12-4.18, P = 0.0221). There was no IABP-related mortality or limb ischemia. Conclusion: No significant difference in early outcomes was observed in hemodynamically stable patients with LMD between prophylactic IABP group and control group. Prophylactic IABP may be unnecessary in patients with LMD undergoing OPCABG.

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Section: Discussionmentioning

confidence: 99%

Prophylactic intra-aortic balloon pump in patients with left main disease undergoing off-pump coronary artery bypass grafting

Zheng

Hua

Zhang

et al. 2020

BMC Cardiovasc Disord

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Kofidis

2011

European Journal of Cardio-Thoracic Surgery

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Cyril (2017) Physical and biological characteristics of multi drug resistance (MDR): an integral approach considering pH and drug resistance in Access from the University of Nottingham repository: http://eprints.nottingham.ac.uk/39780/1/Rauch%20-%20corrections%20accepted%20and %20not%20visible.pdf Copyright and reuse: The Nottingham ePrints service makes this work by researchers of the University of Nottingham available open access under the following conditions. This article is made available under the Creative Commons Attribution Non-commercial No Derivatives licence and may be reused according to the conditions of the licence. For more details see: http://creativecommons.org/licenses/by-nc-nd/2.5/ A note on versions: The version presented here may differ from the published version or from the version of record. If you wish to cite this item you are advised to consult the publisher's version. Please see the repository url above for details on accessing the published version and note that access may require a subscription. For more information, please contact eprints@nottingham.ac.uk Physical and biological characteristics of multi drug resistance (MDR): An integral 1 approach considering pH and drug resistance in cancer. Abstract 20 The role of the Warburg effect in cancer remains to be elucidated with a resurgence in research 21 efforts over the past decade. Why a cancer cell would prefer to use energy inefficient 22

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Off-pump coronary artery bypass grafting in patients with left main disease: is it really safe?

Cited by 2 publications

References 7 publications

Prophylactic intra-aortic balloon pump in patients with left main disease undergoing off-pump coronary artery bypass grafting

Prophylactic intra-aortic balloon pump in patients with left main disease undergoing off-pump coronary artery bypass grafting

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