2016
DOI: 10.1007/s00592-016-0951-0
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Off-pump versus on-pump coronary artery bypass grafting in patients with diabetes: a meta-analysis

Abstract: OFF-CABG significantly reduces the incidence of postoperative cerebrovascular accidents and bleeding complications compared with ON-CABG in diabetic patients. No differences were found regarding mortality, myocardial infarction and renal failure between these two techniques. Our study suggests that OFF-CABG may be an optimal strategy for diabetic patients although adequately powered randomized trials are needed to further verify the finding.

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Cited by 16 publications
(12 citation statements)
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“…Many studies in the literature have shown that the amount of postoperative bleeding is higher in on-pump surgery compared with off-pump surgery, and thus more blood products are used with this technique [van Dijk 2001;Hussain 2016;Wang 2017]. Consistently with the literature, in our study, higher amounts of postoperative bleeding and the use of blood products were observed in the On-Pump Group.…”
Section: Discussionsupporting
confidence: 91%
“…Many studies in the literature have shown that the amount of postoperative bleeding is higher in on-pump surgery compared with off-pump surgery, and thus more blood products are used with this technique [van Dijk 2001;Hussain 2016;Wang 2017]. Consistently with the literature, in our study, higher amounts of postoperative bleeding and the use of blood products were observed in the On-Pump Group.…”
Section: Discussionsupporting
confidence: 91%
“…The inflammatory response to OPCAB may be different but remains significant. 15,16 The occurrence of euDKA in the presence of both CABG and OPCAB in our case series suggests that, in the presence of SGLT2i, any major surgery is a sufficient precipitating factor.…”
Section: Discussionmentioning
confidence: 73%
“…In a meta-analysis including 543,220 diabetic patients and comparing on- and off-pump outcomes, the overall mortality was comparable between the techniques, but OPCAB was associated with significantly decreased incidence of cerebrovascular events (OR 0.45; 95% CI 0.31-0.65; P <0.0001), an impressive 55% reduction [19] .…”
Section: High-risk Patientsmentioning
confidence: 99%