Off‐resonance based assessment of metallic wear debris near total hip arthroplasty

Koch, Kevin M.; Koff, Matthew F.; Bauer, Thomas W.; Shah, Parina; Nencka, Andrew S.; Kaushik, S. Sivaram; Potter, Hollis G.

doi:10.1002/mrm.26807

Cited by 10 publications

(18 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Off‐resonance metallosis scores, or “mScores,” can be generated that take into account the magnitude and size of the identified off‐resonance regions. Higher mScores have been detected in symptomatic individuals 42 . The presence of tissue necrosis, as determined from the evaluation 43 of intra‐operative issue samples, was related to higher mScores.…”

Section: Evaluating Synovial Reactionsmentioning

confidence: 88%

Clinical magnetic resonance imaging of arthroplasty at 1.5 T

Koff

Burge

Potter

2020

Journal Orthopaedic Research

Self Cite

View full text Add to dashboard Cite

Magnetic resonance imaging (MRI) has historically been avoided for the routine clinical evaluation of metal implants at many clinical centers due to the presence of artifact that creates in‐plane and through‐plane distortions and signal intensity voids in generated images. However, when the image acquisition parameters are appropriately modified and advanced multi‐spectral pulse sequences are used, high‐quality diagnostic images can be generated and may be used for diagnosing patients with suspected periprosthetic pathology. MRI provides superior soft‐tissue contrast and excellent sensitivity for mobile water and is, therefore, a valuable tool in the evaluation of these patients, given the increasing prevalence of arthroplasty within the general population. Knowledge of expected normal postoperative appearance in patients with total hip arthroplasty, total knee arthroplasty, and total shoulder arthroplasty facilitates the detection of abnormal findings in this population, as does familiarity with common pathologic conditions encountered in the periprosthetic region. This review article will provide background information regarding the presence of image artifacts, methods to reduce the artifacts, and application of MRI at 1.5 T for evaluating common complications in subjects with total knee arthroplasty, total hip arthroplasty, and total shoulder arthroplasty.

show abstract

Section: Evaluating Synovial Reactionsmentioning

confidence: 88%

Clinical magnetic resonance imaging of arthroplasty at 1.5 T

Koff

Burge

Potter

2020

Journal Orthopaedic Research

Self Cite

View full text Add to dashboard Cite

show abstract

“…Tissue magnetism within the defined region was estimated utilizing multispectral raw MAVRIC‐SL data analyzed using previously developed methods 26 . Briefly, the procedure implemented included: …”

Section: Methodsmentioning

confidence: 99%

“…Following the background removal, an off‐resonance detection threshold frequency was set below which particulate deposits cannot be distinguished from normal fat‐water tissue transitions (225 Hz at 1.5 T). Computation of off‐resonance metallosis score, or “mScore," using cluster‐based off‐resonance analysis 26 . As the larger pockets of debris deposition tended to have higher off‐resonance values, cluster volumes and off‐resonance frequency thresholds were incorporated to define the nonlinear grading “mScore" as an exponential function of the two computed metrics.…”

Section: Methodsmentioning

confidence: 99%

“…Moreover, it was hypothesized in this study that the observed magnetism signatures from metal debris are driven by disassociated Co ions. This fundamental hypothesis was supported by the relative strength of magnetism mScore correlations with necrosis and its weak correlation with histological scores for optically visible large metal particles 26 …”

Section: Introductionmentioning

confidence: 93%

“…The fundamental premise is that implanted THA devices alter the static magnetic field of MRI scanner and, in turn, the local Larmor frequencies detected by MRI equipment. As a result, raw MRI data can be decoded to detect these exceptionally small magnetic field shifts derived from both the hip prosthesis and the implant‐induced metal debris in periprosthetic tissue 19,26 …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Multivariate use of MRI biomarkers to classify histologically confirmed necrosis in symptomatic total hip arthroplasty

Sherafati

Bauer

Potter

et al. 2020

Journal Orthopaedic Research

Self Cite

View full text Add to dashboard Cite

The failure of total hip arthroplasty (THA) is commonly associated with the necrosis of the periprosthetic tissue. To date, there is no established method to noninvasively quantify the progression of such necrosis. Magnetic resonance imaging (MRI) of soft tissues near implants has undergone a recent renaissance due to the development of multispectral metal‐artifact reduction techniques. Advanced analysis of multispectral MRI has been shown capable of detecting small magnetism effects of metallic debris in periprosthetic tissue. The purpose of this study is to demonstrate the diagnostic utility of these MRI‐based tissue‐magnetism signatures. Together with morphological MRI metrics, such as synovial volume and thickness, these measurements are utilized as biomarkers to noninvasively detect soft‐tissue necrosis in symptomatic THA patients (N=78). All subjects underwent an advanced MRI scan before revision surgery and tissue biopsies utilized for necrosis grading. Statistical analyses demonstrated a weak, but significant positive correlation (P = .04) between MRI magnetism signatures and necrosis scores, while indicating no meaningful association between the latter and serum cobalt and chromium ion levels. Receiver‐operating characteristic (ROC) analyses were then performed based on uni‐ and multivariate logistic regression models utilizing the measured MRI biomarkers as predictors of severe necrosis. The area under the curve of the ROC plots for MRI biomarkers as combined predictors were found to be 0.70 and 0.84 for cross‐validation and precision‐recall tests, respectively.

show abstract

Lubricated sliding of CFRPEEK/AlCrN film tribo-pair and its effect on the mechanical properties and structural integrity of the AlCrN film

Patnaik

Maity

Kumar

2021

Materials Chemistry and Physics

View full text Add to dashboard Cite

Off‐resonance based assessment of metallic wear debris near total hip arthroplasty

Abstract: Magnetostatic simulations, theoretical principles, and preliminary histological trends suggest that disassociated cobalt is the source of the observed off-resonance signature. Magn Reson Med 79:1628-1637, 2018. © 2017 International Society for Magnetic Resonance in Medicine.

Cited by 10 publications

References 46 publications

Clinical magnetic resonance imaging of arthroplasty at 1.5 T

Clinical magnetic resonance imaging of arthroplasty at 1.5 T

Multivariate use of MRI biomarkers to classify histologically confirmed necrosis in symptomatic total hip arthroplasty

Lubricated sliding of CFRPEEK/AlCrN film tribo-pair and its effect on the mechanical properties and structural integrity of the AlCrN film

Contact Info

Product

Resources

About