Office closure of tympanic perforations: a new approach

Repair of Traumatic Myringorupture

“…2 and 3), the treatment herein described must be carried out within this time. 5 Otherwise, after 4 days, approxima¬ tion of the edges is useless due to epithelialization and "fistula formation," and another technique, such as the "office closure" treat¬ ment of Derlacki should be used.6…”

Gelfoam plug tympanoplasty concomitant with removal of retained ventilation tubes

“…The rationale for excision of the edges of the perforation, described by Juers [16], after removal of long-standing tubes in the TM, is to ablate the squamous epithelium covering the margins of the perforation which might otherwise prevent complete closure, and to stimulate TM growth.…”

Closure of Small Central Perforations of Tympanic Membrane With Gelfilm Patch and Application of Platelet Rich Plasma Versus Chemical Cauterization: A Comparative Study

“…Juers reported a closure rate of 85-90% in selected cases with an average of five to six treatments. [19,20] Derlacki reported a 75% closure rate in 1227 patients, requiring an average of more than 14 office treatments carried out at biweekly intervals. [21] Dunlap treated 15 cases with 100% closure rate; however, there were 3-33 treatments at 2-week intervals.…”