Ofuji papuloerythroderma in an elderly woman with atopic erythroderma

Camacho, Francisco Gómez; Garcia-Hernandez, M. J.; Muñoz‐Pérez, M.A.; Mazuecos, J; Sotillo, I.

doi:10.1046/j.1468-3083.2001.02532.x

Cited by 15 publications

(10 citation statements)

References 13 publications

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“…One hundred twenty-five [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51], 25 [52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73], and 18 cases of PEO [74,75,76,77,78,79,80,81,82,83,84,85,86,87] were identified, respectively, for a grand total of 170 cases (including the present 2) as of July 31, 2009. Six case reports were excluded as redundancy with later articles was suspected [88,89,90,91,92]. ...…”

Section: Resultsmentioning

confidence: 99%

Papuloerythroderma 2009: Two New Cases and Systematic Review of the Worldwide Literature 25 Years after Its Identification by Ofuji et al.

Torchia

Miteva

et al. 2010

Dermatology

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Background: Even after the description of papuloerythroderma of Ofuji (PEO) in 1984, little is known about this clinical entity. Objective:To report on 2 new cases of PEO and review of the worldwide literature on this topic. Methods: Article citations were searched on several biomedical search engines (PubMed, EMBASE, SCOPUS, Google Scholar). Papers were retrieved either online or in print. Results: A grand total of 170 PEO cases were identified. Most patients were older than 55 years and of Asian or white descent, with an overall male/female ratio of 4.0. Itch and the deck-chair sign were observed in all patients. Peripheral eosinophilia, lymphocytopenia and increased serum IgE were common findings. Histopathology mostly showed aspecific inflammation, while 17 showed histological features of cutaneous T-cell lymphoma (CTCL). Atopy, malignancies, infections and drugs were rarely linked to PEO. Conclusion: PEO represents a rather monomorphous entity both clinically and, with the remarkable exception of CTCL, also histologically. Nonetheless, no causative factor could be identified in the vast majority of cases. An etiological classification and diagnostic criteria are proposed in the attempt to contribute framing this puzzling clinical entity.

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Section: Resultsmentioning

confidence: 99%

Papuloerythroderma 2009: Two New Cases and Systematic Review of the Worldwide Literature 25 Years after Its Identification by Ofuji et al.

Torchia

Miteva

et al. 2010

Dermatology

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“…The term ‘Ofuji papuloerythroderma’ should not be used when we do not know the aetiology of the dermatosis, and the use of the term ‘papuloerythroderma’ should be limited to cases with a definite and appropriate aetiology 12 …”

Section: Discussionmentioning

confidence: 99%

Ofuji papuloerythroderma evolving to cutaneous T‐cell lymphoma

Martínez-Barranca

García‐Morales

et al. 2004

Acad Dermatol Venereol

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Ofuji papuloerythroderma is an uncommon entity of unknown aetiology, characterized by a pruritic eruption of widespread, red-brown, flat papules that leads to spare skin folds. A number of cases have been described associated with tumour pathology, mainly cutaneous T-cell lymphomas. We report a new case of Ofuji papuloerythroderma evolving to cutaneous T-cell lymphoma in an 85-year-old woman who had been previously diagnosed with papuloerythroderma 7 years previously.

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“…Controversial results with various treatments have been reported. Systemic corticosteroids are usually effective, but relapse during dose tapering and corticosteroid‐related adverse events often complicate management of this condition 4,5,13,16,17 . Promising results have been reported with cyclosporin in two cases who were unresponsive to other treatment modalities 19,20 .…”

Section: Discussionmentioning

confidence: 99%

“…The disease occurs primarily in elderly men and is often associated with lymphadenopathy, peripheral blood eosinophilia, lymphopenia and elevated immunoglobulin E (IgE) levels 2,3 . The etiopathogenesis of papuloerythroderma of Ofuji (PEO) is still unknown, but it has been suggested that it can be an unusual variant of many inflammatory dermatoses such as atopic dermatitis in elderly patients 4,5 . PEO can be a cutaneous sign of internal malignancy, 6–8 acquired immunodeficiency syndrome (AIDS), 9,10 hypersensitivity to drugs, 10 or a manifestation of cutaneous lymphoma 11–15 .…”

Section: Introductionmentioning

confidence: 99%

“…PEO can be a cutaneous sign of internal malignancy, 6–8 acquired immunodeficiency syndrome (AIDS), 9,10 hypersensitivity to drugs, 10 or a manifestation of cutaneous lymphoma 11–15 . Various therapeutic approaches including systemic corticosteroids, 4,5,9,13,16–18 cyclosporin, 19,20 azathioprine, 21 interferon alpha, 22 psoralen plus UVA (PUVA), 7,10,11,13,15,18,23–27 systemic retinoids, 6,22,28 and retinoid plus PUVA (Re‐PUVA) 12,14,15 have been used in the treatment of the disease with varying success.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Treatment of papuloerythroderma of Ofuji with Re‐PUVA: a case report and review of the therapy§

Mutluer¹,

Yerebakan²,

Alpsoy³

et al. 2004

Acad Dermatol Venereol

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Papuloerythroderma of Ofuji (PEO) is a disease of elderly men, characterized by intensely pruritic and widespread, red, flat-topped papules with sparing of the body folds and creases (the so-called 'deck-chair' sign). The etiopathogenesis of the disease remains unknown. Psoralen plus UVA (PUVA), topical and systemic corticosteroids, etretinate, cyclosporin and interferon are the main approaches in the treatment of this rare disease. A case of PEO in a 60-year-old man who responded to retinoid plus PUVA (Re-PUVA) treatment is reported here and a review of the therapy with other relevant cases is presented.

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Ofuji papuloerythroderma in an elderly woman with atopic erythroderma

Cited by 15 publications

References 13 publications

Papuloerythroderma 2009: Two New Cases and Systematic Review of the Worldwide Literature 25 Years after Its Identification by Ofuji et al.

Papuloerythroderma 2009: Two New Cases and Systematic Review of the Worldwide Literature 25 Years after Its Identification by Ofuji et al.

Ofuji papuloerythroderma evolving to cutaneous T‐cell lymphoma

Treatment of papuloerythroderma of Ofuji with Re‐PUVA: a case report and review of the therapy§

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