Oksitosin Düzeyi ile Postpartum Depresyon Arasındaki İlişki

Abstract

Psychological and social changes during pregnancy, birth and postpartum periods may lead to the development of mental disorders. Postpartum depression is the most common psychological disorder seen in the postpartum period, and the treatment of it is very significant for the mother and the baby. Physical/biological, psychological, obstetric, pediatric and socio-economic status, genetic factors and hormonal changes are the risk factors of postpartum depression. Causing attachment, mental health and behavioral effects as well obstetric effects, oxytocin hormone is substantially crucial in postpartum depression. It is reported in the literature that there is a relationship between oxytocin level and postpartum depression. It is thought that usage of oxytocin levels as a predictive biomarker will offer an opportunity early diagnosis and treatment of postpartum depression, and will be a useful approach to minimize its impacts on family health.

Are pregnancy and postpartum oxytocin level a predictive biomarker for postpartum depression?

“…Important changes happen in the oxytocin (OT) levels in pregnancy, labor, and postpartum periods. 4,5 OT level increase in the late pregnancy and it is the peak in labor. The OT level decreases slowly from labor to postpartum 12th week and returns to its pre-pregnancy level.…”