Olanzapine in the treatment of Capgras Syndrome: a case report

Torales, Júlio; Rodríguez, Hugo; Arce, Andrés; Moreno, Martín; Riego, Viviana; Chávez, Emilia; Capurro, Marcos

doi:10.1080/17542863.2013.775782

Cited by 5 publications

(4 citation statements)

References 16 publications

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“…According to the results of the case studies in the literature, CS patients are sometimes responsive to typical and atypical antipsychotics such as olanzapine, risperidone, quetiapine, sulpiride, trifluoperazine, and pimozide [20]. CS is based on antipsychotics, antidepressants, anticonvulsant, and benzodiazepines considering patient needs and characteristics, but no control trials are available [49]. In the literature, there have been reported cases with a diagnosis of organic or functional delusional disorder associated with CS whose DMS responded well to pimozide that is well known for the treatment of monosymptomatic delusional disorders [49].…”

Section: Treatment Considerationsmentioning

confidence: 99%

“…CS is based on antipsychotics, antidepressants, anticonvulsant, and benzodiazepines considering patient needs and characteristics, but no control trials are available [49]. In the literature, there have been reported cases with a diagnosis of organic or functional delusional disorder associated with CS whose DMS responded well to pimozide that is well known for the treatment of monosymptomatic delusional disorders [49]. Experience with the new generation of atypical antipsychotics for the treatment of CS is quite limited.…”

Section: Treatment Considerationsmentioning

confidence: 99%

“…Although for patients manifesting any psychotic disorder, atypical antipsychotics are usually recommended because of the reduced risk of adverse effects [6,47]. A crucial point of a case report is the positive outcome in response to antipsychotic medication [olanzapine] [49]. The combination of antipsychotic drug therapy and selective serotonin reuptake inhibitor (SSRI) may produce a positive outcome in patients with CS [16].…”

Section: Treatment Considerationsmentioning

confidence: 99%

“…Electroconvulsive therapy (ECT) has been reported to benefit either alone or in conjunction with antipsychotics, mood stabilizer, or antidepressant medication in patients with CS. It has been suggested that ECT provides permanent effective control of CS [42,47,49].…”

Section: Treatment Considerationsmentioning

confidence: 99%

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What is Capgras Syndrome? Diagnosis and Treatment Approach

Koc¹,

Hocaoğlu²

2021

Anxiety Disorders - The New Achievements

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Capgras delusion is a complex psychopathological phenomenon that presents in a wide range of psychiatric and neurological disorders with differing patterns dependent on the main etiology. An underlying neurological disease should be suspected where the delusion concerns a spouse or inanimate objects and is associated with visual hallucinations, while a functional disorder is suggested by multiple imposters, strangers, additional delusions, and auditory hallucinations. Misidentifications in Capgras syndrome (CS) are fixed false beliefs and, therefore, represent true delusions. Even if when patients are confronted over and over with the illogical nature of the delusion, they keep their beliefs. Surprisingly, patients may show implicit or explicit awareness of their true situation. Some research suggests that a considerable number of patients with CS have some awareness of the bizarre nature of the misidentification delusions and therefore tend not to report them, especially during initial interviews when they are less likely to be confident with the clinician. Specific questions and interventions may assist clinicians in successfully identifying patients with CS. In a series of interviews with these patients, some focus on identifying CS, rather than a single interview which is likely to increase the detection of the delusional misidentification. The clinician should always be mindful of the risk of aggression and homicide in CS.

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Section: Treatment Considerationsmentioning

confidence: 99%

Section: Treatment Considerationsmentioning

confidence: 99%