2015
DOI: 10.1007/s40519-015-0247-3
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Olanzapine-induced atypical neuroleptic malignant syndrome in an adolescent man with anorexia nervosa

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Cited by 14 publications
(7 citation statements)
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“…Biochemical side effects were closely monitored and were felt to be more related to refeeding processes than to medication [141]. Thirteen case reports (Table 24) have also been published [42,[143][144][145][146][147][148][149][150][151][152][153][154]. Pisano and colleagues [143] reported on five cases of adolescents with AN treated with 2.5 to 7.5 mg of olanzapine.…”
Section: Olanzapinementioning
confidence: 99%
“…Biochemical side effects were closely monitored and were felt to be more related to refeeding processes than to medication [141]. Thirteen case reports (Table 24) have also been published [42,[143][144][145][146][147][148][149][150][151][152][153][154]. Pisano and colleagues [143] reported on five cases of adolescents with AN treated with 2.5 to 7.5 mg of olanzapine.…”
Section: Olanzapinementioning
confidence: 99%
“…The symptoms consisted of high fever (max 40 °C), leukocytosis, elevated levels of creatine kinase (CPK), and fluctuation in his mental state. Although the drug was discontinued, NMS developed again after 30 days [ 31 ].…”
Section: Resultsmentioning
confidence: 99%
“…No clear-cut, olanzapine-related adverse effects were reported by five papers [ 25 , 26 , 27 , 28 , 30 ]. A severe side effect was reported in a sole case report where the onset of Neuroleptic neuroleptic malignant syndrome after two days of treatment is described [ 31 ]. Liver enzymes [ 21 , 22 ] and lipid profile/cholesterol elevation [ 21 , 24 ], itching [ 23 ], headache [ 20 ] and sedation/somnolence [ 20 , 21 , 23 , 24 , 29 ] were reported, with only one case of QTc elongation [ 46 ].…”
Section: Discussionmentioning
confidence: 99%
“…Safety profile of olanzapine treatment in AN has also been a point of interest in our study. There are few case reports showing adverse effects including neuroleptic malignant syndrome, hypoglycemia, hyperglycemia, morning sedation, and heart block [34,36,37,42]. However, most studies report no significant adverse reactions.…”
Section: Qualitative Evaluationmentioning
confidence: 99%