Olecranon Bursitis Caused by<i>Candida parapsilosis</i>in a Patient with Rheumatoid Arthritis

Gamarra-Hilburn, Carla F.; Ríos, Grissel; Vilá, Luis M.

doi:10.1155/2016/2019250

Cited by 5 publications

(1 citation statement)

References 15 publications

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“…[41] 2016 1 Kadın/25 Kalça C. albicans İmmünosüpresyon FLK İyileşme Gamarra-Hilburn ve ark. [42] 2016 1 Kadın/68 Dirsek C. parapsilosis Romatoid artrit CAS→ FLK İyileşme Çevik ve ark. [43] 2016 1…”

Section: Mi̇ka→ Flkunclassified

Osteoarticular Candida Infection: Case Reports and Literature Review

Aksoy¹,

Aydın²,

Ertuğrul³

et al. 2019

mjima

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Funguslara bağlı kemik eklem enfeksiyonları nadirdir. Kandida türlerine bağlı osteomiyelit de oldukça nadir görülen bir durumdur. Etken olarak en sık Candida albicans görülür, ancak son yıllarda non-albicans Candida'ların da osteomiyelitlerde sıklığının arttığı bildirilmektedir. Bu yazıda nonalbicans Candida osteomiyeliti olan üç olgu sunuldu. Osteoartiküler tutuluma bakıldığında olguların birinde lomber vertebra, birinde el, diğerinde ise ayak osteomiyeliti vardı. Olguların üçünde diabetes mellitus ve uzun süreli antibiyotik kullanımı ortak risk faktörleriydi. Vertebral osteomiyelit olan olguda ayrıca cerrahi girişim ve yabancı cisim varlığı diğer risk faktörleriydi. Olguların tanısında manyetik rezonans görüntüleme kullanıldı ve alınan derin doku kültüründe etken izole edildi. Tüm olgulara cerrahi debritman yapılarak altı hafta ile 24 hafta arasında değişen sürede antifungal tedavi verildi. Olgularda klinik ve radyolojik takiplerde enfeksiyon tekrarlamadı. Ayağında osteomiyeliti olan olgu akut serebrovasküler hastalık nedeni ile eksitus oldu. Çalışmamızda Nisan 2010-Haziran 2019 tarihleri arasında osteoartiküler Candida enfeksiyonu ile ilgili literatür taraması yapıldı ve 44 olgu derlendi. Çalışmamızda bu olguları sunmadaki amacımız, kandidaya bağlı osteoartiküler enfeksiyonlara dikkati çekmek ve etken tanımlanmasıyla hedefe yönelik tedavinin önemini vurgulamaktır. Anahtar Kelimeler: Spondilodiskit, flukonazol, kaspofungin, sistematik derleme, lipozomal amfoterisin b Fungal infections in the bones and joints are rare. Candida spp. osteomyelitis is also a very rare entity. The most common pathogen is Candida albicans, but an increase in the incidence of non-albicans Candida osteomyelitis has been reported in recent years. Herein, we present three patients with non-albicans Candida osteomyelitis. Osteoarticular involvement occurred in the lumbar vertebrae in one patient, in the hand in one patient, and the foot in the other patient. Diabetes mellitus and long-term antibiotic use were common risk factors in all three cases. In the patient with vertebral osteomyelitis, surgical intervention and foreign body were other risk factors. Magnetic resonance imaging was used in the diagnosis and the pathogens were isolated from deep tissue cultures. Surgical debridement was performed in all cases and antifungal treatment was given for 6-24 weeks. There was no reinfection or relapse during clinical and radiological follow-up. The patient with osteomyelitis of the foot died due to to acute cerebrovascular disease. In our study, the literature review for publications related to osteoarticular Candida infection was made between April 2010 and June 2019 and 44 cases are reviewed. Our aim in this study was to draw attention to Candida osteoarticular infections and to emphasize the importance of targeted treatment by defining the pathogen.

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Section: Mi̇ka→ Flkunclassified

Osteoarticular Candida Infection: Case Reports and Literature Review

Aksoy¹,

Aydın²,

Ertuğrul³

et al. 2019

mjima

View full text Add to dashboard Cite

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Fungal Olecranon Bursitis in an Immunocompetent Patient by Knoxdaviesia dimorphospora sp. nov.: Case Report and Review

et al. 2017

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Bursitis is a common medical condition that can occur either with or without infection. We present a case of fungal olecranon bursitis in an immunocompetent individual caused by the new species Knoxdaviesia dimorphospora. It is a dematiaceous filamentous fungus characterized by the production of two different conidia: hyaline and cylindrical, which rise up from phialidic conidiogenous cells located in the upper part of differentiated and unbranched conidiophores, and pale brown and ellipsoidal conidia produced by phialidic conidiogenous cells which are born directly on hyphae. In addition to its morphological peculiarities, the novelty of the fungus was confirmed by sequence analysis of the internal transcribed spacer (ITS) regions and D1/D2 domains of the 28S of the nuclear rRNA gene. The fungal infection was confirmed by cytological examination and repeated cultures. The infection was resolved by surgical debridement and drainage, and the patient presented a complete functional recovery 3 months later. The in vitro antifungal susceptibility to this new human opportunist is provided, terbinafine being the drug with the most potent activity.

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