Olfactory changes after endoscopic sinus surgery in patients with chronic rhinosinusitis

Oka, Hiroyuki; Tsuzuki, Kenzo; Takebayashi, Hironori; Kojima, Yusuke; Daimon, Takashi; Sakagami, Masafumi

doi:10.1016/j.anl.2012.12.001

Cited by 62 publications

(55 citation statements)

References 15 publications

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“…In our experience, VAS also significantly decreased after ESS both in the ECRS group and no-ECRS group [36]. Thus, our ESS showed favorable results for CRS patients refractory to medical therapies.…”

Section: Discussionmentioning

confidence: 62%

“…Olfactory tests were performed using the T&T olfactometer and intravenous olfaction test, both of which are covered by health insurance and are commonly used for olfactory examination in our country [36]. The T&T olfactory test consists of 5 odorants: (i) β-phenylethyl alcohol, which smells like a rose; (ii) methyl cyclopentenolone, which smells like burning; (iii) isovaleric acid, which smells like sweat; (iv) γ-undecalactone, which smells like fruit; and (v) skatole, which smells like garbage (Takasago Industry Ltd., Tokyo, Japan).…”

Section: Methodsmentioning

confidence: 99%

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Nasal Symptom Questionnaire: Our Proposed Scoring System and Prognostic Factors in Chronic Rhinosinusitis

Saito

Tsuzuki

Nishikawa

et al. 2018

ORL

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Objectives: We aimed to verify the usefulness of our proposed nasal symptom questionnaire (NSQ) scoring system and to determine predictors linked to the improvement in nasal symptoms in chronic rhinosinusitis (CRS) patients undergoing endoscopic sinus surgery (ESS). Patients and Methods: Ninety-one CRS patients undergoing ESS and 144 volunteers with results of NSQ available were enrolled. The NSQ consists of 10 items. Receiver-operating-characteristic (ROC) curve, area under the ROC curve (AUC), internal consistency, and test-retest reproducibility of the NSQ were analyzed. The relationship of the NSQ score with the visual analogue scale (VAS) was examined. After classifying into two groups, i.e., (i) “improvement group” and (ii) “no-improvement group,” factors linked to the improvement in NSQ after ESS were investigated. Results: ROC-AUC (0.9318), the Cronbach α coefficient (0.8696), and the test-retest coefficient (0.8131) showed high reliability. NSQ score significantly correlated with VAS in both pre- (p < 0.0001, r_s = 0.6007) and postoperative stages (p < 0.0001, r_s = 0.5975). The postoperative NSQ scores significantly decreased compared with baseline levels (p < 0.0001). In multivariate analysis, the computed tomography (CT) score by the Lund-Mackay scoring system revealed to be significant (p = 0.0481). Conclusion: Our proposed NSQ scoring system was well verified. The CT score can be helpful for predicting the improvement in nasal symptoms after ESS in CRS patients.

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Section: Discussionmentioning

confidence: 62%

Section: Methodsmentioning

confidence: 99%

Nasal Symptom Questionnaire: Our Proposed Scoring System and Prognostic Factors in Chronic Rhinosinusitis

Saito

Tsuzuki

Nishikawa

et al. 2018

ORL

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“…As postoperative treatment, medical therapy with antibiotics, mucinolytics, antiallergic agents, and nasal irrigation with saline was performed for each patient until the postoperative sinonasal mucosal condition had stabilized, as we reported previously [15]. Postoperative intranasal findings were evaluated using the endoscopic score (E score) [16].…”

Section: Methodsmentioning

confidence: 99%

Clinical Features of Patients Treated with Endoscopic Sinus Surgery for Posttraumatic Paranasal Sinus Mucocele

Kojima

Tsuzuki²,

Yukitatsu³

et al. 2015

ORL

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Aim: The purpose of this study was to analyze the clinical features of patients with posttraumatic paranasal sinus mucocele (PSM). Subjects and Methods: Between 2009 and 2013, we performed endoscopic sinus surgery (ESS) on 68 patients with PSM at the Department of Otolaryngology - Head and Neck Surgery at Hyogo College of Medicine. Five male patients (age range, 45-76 years) with posttraumatic PSM were analyzed retrospectively. Diagnosis was based on the history of injury and radiological findings. Results: Posttraumatic PSM was found in 7% (5/68) of patients. The mean interval from injury to diagnosis was 28.4 years. All patients had frontal sinus mucocele. Four patients had symptoms of headache, diplopia, visual field defect, and forehead swelling, and 1 patient was asymptomatic. ESS was performed under general anesthesia in all cases, and the symptoms improved postoperatively. Reoperation was required in 1 patient (20%) because headache developed with obstruction of the frontal drainage route 7 months after ESS. Conclusions: Posttraumatic PSM was the least frequent form of PSM and was located predominantly in the frontal sinus, causing symptoms long after the forehead injury. The important lessons to be learned for treating posttraumatic PSM are to obtain a detailed history and to enlarge the route to the cyst to avoid its recurrence.

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“…This analysis is unique in that it represents the only prospective, multi-institutional, comparative effectiveness study. Prior study of CRS and olfaction is predominantly prospective cohort studies that lack a medical control arm [32][33][34] or do not conform to current treatment protocols [35]. There are two important caveats to place on these results.…”

Section: Clinical Outcomesmentioning

confidence: 99%

Outcomes of Surgical Treatment of Chronic Rhinosinusitis

DeConde

Alt

2015

Curr Otorhinolaryngol Rep

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Since the introduction of endoscopic sinus surgery (ESS) for treatment of chronic rhinosinusitis (CRS) over 25 years ago, there has been an effort to quantify the effectiveness of this intervention. Within the last few years, the field has matured to a point where study designs are able to accurately capture the impact of ESS relative to continued medical therapy on the CRS disease process and quality-of-life (QOL). These comparative effectiveness studies demonstrate superior effectiveness of ESS over medical therapy at mean reduction of disease burden as measured by comprehensive disease-specific QOL questionnaires. As outcomes from large comparative effectiveness studies accumulates, and a more complete understanding of the many variables that contribute to and influence CRS, the potential to build predictive models based on baseline characteristics might allow for forecasting of treatment successes and failures.

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Olfactory changes after endoscopic sinus surgery in patients with chronic rhinosinusitis

Cited by 62 publications

References 15 publications

Nasal Symptom Questionnaire: Our Proposed Scoring System and Prognostic Factors in Chronic Rhinosinusitis

Nasal Symptom Questionnaire: Our Proposed Scoring System and Prognostic Factors in Chronic Rhinosinusitis

Clinical Features of Patients Treated with Endoscopic Sinus Surgery for Posttraumatic Paranasal Sinus Mucocele

Outcomes of Surgical Treatment of Chronic Rhinosinusitis

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