OLGA‐ and OLGIM‐based staging of gastritis using narrow‐band imaging magnifying endoscopy

Saka, Akiko; Yagi, Kazuichi; Nimura, Satoshi

doi:10.1111/den.12483

Cited by 47 publications

(41 citation statements)

References 14 publications

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“…In another study, NBI was compared to the operative link for gastritis assessment and for gastric intestinal metaplasia assessment (OLGA and OLGIM, respectively) staging systems which can separate low‐ and high‐risk groups for gastric cancer (GC). The degree of correspondence between the two methods was 89.1% . Furthermore, NBI enables the sampling of targeted biopsies (“site specific”) vs standard site biopsies; this method was shown to be more effective for both detection of H. pylori and detection of premalignant lesions …”

Section: Invasive Testsmentioning

confidence: 97%

Diagnostic of Helicobacter pylori infection

et al. 2016

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There is progress in endoscopy techniques. While it is not yet possible to detect Helicobacter pylori directly in the stomach, it becomes easier to detect the mucosal changes induced by the bacteria. Some small changes can also increase the sensitivity of the invasive tests, for example culture or histology, but the wide use of proton-pump inhibitors has a negative impact on these tests. Only molecular methods are able to detect a limited load of bacteria, especially by using real-time PCR but also with new methods, for example dual-priming oligonucleotide-based PCR, loop-medicated isothermal amplification, droplet-digital PCR or a multiple genetic analysis system. Among the noninvasive tests, urea breath test remains a test of major interest, while there are attempts to develop an ammonia breath test and other nanosensor devices. A new antigen stool test, a chemoluminescence immunoassay using the LIAISON apparatus has also been tested for the first time with success. Despite its limitations, serology remains the most popular test to detect H. pylori antibodies. It also allows pepsinogen dosage which is of interest for detecting atrophy.

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Section: Invasive Testsmentioning

confidence: 97%

Diagnostic of Helicobacter pylori infection

et al. 2016

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“…The diagnostic yield of white-light, chromo, and NBI endoscopy for intestinal metaplasia has been discussed previously [11,19,20]. In white-light endoscopy, villous mucosa and whitish mucosa were indicative of intestinal metaplasia [19].…”

Section: Discussionmentioning

confidence: 99%

“…Meanwhile, narrow-band imaging (NBI) endoscopy is reportedly fairly accurate for the diagnosis of atrophy and intestinal metaplasia [9-11]. In our previous study, the micro-mucosal pattern in the gastric corpus was classified as foveolar or groove type using magnifying NBI endoscopy.…”

Section: Introductionmentioning

confidence: 99%

Investigation of mucosal pattern of gastric antrum using magnifying narrow-band imaging in patients with chronic atrophic fundic gastritis

Yamasaki

Uedo²,

Kanzaki

et al. 2017

aog

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BackgroundMagnifying narrow-band imaging (M-NBI) can reportedly help predict the presence and distribution of atrophy and intestinal metaplasia in the gastric corpus. However, the micro-mucosal pattern of the antrum shown by M-NBI differs from that of the corpus. We studied the distribution and histology of the micro-mucosal pattern in the antrum based on magnifying endoscopy.MethodsEndoscopic images of the greater curvature of the antrum were evaluated in 50 patients with chronic atrophic fundic gastritis (CAFG). The extent of CAFG was evaluated by autofluorescence imaging. The micro-mucosal pattern was evaluated by M-NBI and classified into groove and white villiform types. The localization of white villiform type mucosa was classified into three types in relation to the areae gastricae: null, central, and segmental types. Biopsies were taken from regions showing different micro-mucosal patterns. Associations among the extent of CAFG, micro-mucosal pattern, and histology were examined.ResultsAs the extent of CAFG increased, the proportion of white villiform type mucosa increased, whereas that of groove type mucosa decreased (P=0.022). In patients with extensive CAFG, most of the areae gastricae was composed of the segmental or central type of white villiform type mucosa (P=0.044). The white villiform type mucosa had significantly higher grades of atrophy (P=0.002) and intestinal metaplasia (P<0.001) than did the groove type mucosa.ConclusionWhite villiform type mucosa is indicative of atrophy and intestinal metaplasia in the gastric antrum. It extends to the whole or central part of the areae gastricae as CAFG becomes more extensive.

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“…Thus, taking several biopsy specimens for gastritis staging tends to be avoided. Furthermore, this approach for gastritis staging imposes a considerable burden on endoscopist, pathologist and substantially increases medical costs and procedure time [18] . Taken together these data suggested the importance of real time diagnosis of atrophic gastritis as well as IM and staging of gastric cancer risk, during endoscopic surveillance for gastric precancerous lesions.…”

Section: Discussionmentioning

confidence: 99%

“…Taken together these data suggested the importance of real time diagnosis of atrophic gastritis as well as IM and staging of gastric cancer risk, during endoscopic surveillance for gastric precancerous lesions. Recently Saka et al, concluded that staging of gastritis using NBI-magnifying endoscopy is able to approximate that determined by OLGA and OLGIM staging and is expected to be a practical approach that can replace staging based on the histology of biopsy specimen [18] . However examining the whole stomach by NBI-ME is difficult, time consuming, need special patient preparation and not suitable for patients screening.…”

Section: Discussionmentioning

confidence: 99%