Oligodendrogliomas I. A clinical study of cerebral oligodendrogliomas

Abstract

Fifty-four patients with oligodendroglioma presented in the past 15 years. In contrast to some widely taught concepts, oligodendrogliomas occured largely in the frontotemporal area of both cerebral hemispheres with two peaks of age incidence: one small peak in childhood, and the highest incidence in the middle-aged adult. Seizures, either major and/or minor, were the most common clinical manifestations (average 87%). Cerebral angiography and pneumography were the most reliable and useful diagnostic procedures, as well as the promising CAT scan. All 24 patients who underwent combined modalities of treatment with radical surgery and postoperative radiation therapy survived at least five years, and 2 out of 11 patients treated by surgery alone failed to survive the five-year follow-up period in addition to two recurrences. Postoperative radiation treatment is considered quite effective and indicated in most cases because complete removal of the tumor is not always possible.

Primary Oligodendroglioma of the Lateral Ventricle: Computed Tomography and Magnetic Resonance Imaging Findings

“…Intraventricular oligodendrogliomas frequently occur in the third and fourth decades of life. While it has previously been stated that intraventricular oligodendrogliomas present at an earlier age (5) several recent series showed no significant age difference between the parenchymal and intraventricular tumors (3)(4)(5). Although seizure is the most common presenting symptom of hemispheric oligodendrogliomas (4), the intraventricular variety commonly causes signs of increased intracranial pressure (3,5).…”

Anaplastic Oligodendroglioma in an Adolescent Male; A rare case Report and Review of the Literature

“…They represent the third most common glioma overall, accounting for 2%-5% of primary brain tumours and 5%-18% of all glial neoplasms [1][2][3][4] . The tumour accounts for less than 1% of paediatric central nervous system neoplasms [5] .…”

“…Patients with anaplastic tumours are usually slightly older (peak age, sixth and seventh decades) than those with well-differentiated oligodendrogliomas [8,9] . A small percentage arises in children, accounting for a second smaller age peak at 6-12 years [3,4,[10][11][12] . Incidence of its anaplastic variant is further lower.…”

Valor pronóstico de los marcadores tumorales de proliferación celular y angiogénesis en los oligodendrogliomas

“…Los oligodendrogliomas constituyen entre el 2 y el 4% de los tumores cerebrales primarios 1, 2 y del 4 al 18% de los gliomas intracraneales según las diferentes series 3,4 , siendo más frecuentes en la edad adulta (entre 26 y 46 años) y en los varones 2,5 . Existen diversas clasificaciones histopatológicas de estos tumores, que los dividen en cuatro grados 6,7 , tres grados 8 o preferentemente basado en su pronóstico dos grados 9,10 , lo que coincide con la OMS que los clasifica en bien diferenciados y anaplásicos 11,12 .…”